Results 21 to 30 of about 903,165 (318)

On testing global optimization algorithms for space trajectory design [PDF]

open access: yes, 2008
In this paper we discuss the procedures to test a global search algorithm applied to a space trajectory design problem. Then, we present some performance indexes that can be used to evaluate the effectiveness of global optimization algorithms.
Marco Locatelli   +10 more
core   +3 more sources

A hybrid multiagent approach for global trajectory optimization [PDF]

open access: yes, 2008
In this paper we consider a global optimization method for space trajectory design problems. The method, which actually aims at finding not only the global minimizer but a whole set of low-lying local minimizers(corresponding to a set of different design
Vasile, M.   +4 more
core   +1 more source

Optimal Monitoring Design [PDF]

open access: yesEconometrica, 2020
This paper considers a Principal–Agent model with hidden action in which the Principal can monitor the Agent by acquiring independent signals conditional on effort at a constant marginal cost. The Principal aims to implement a target effort level at minimal cost. The main result of the paper is that the optimal information‐acquisition strategy is a two‐
Georgiadis, George, Szentes, Balazs
openaire   +1 more source

Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope

open access: yesActa Pharmaceutica Sinica B, 2022
The proteolysis targeting chimeras (PROTACs) technology has been rapidly developed since its birth in 2001, attracting rapidly growing attention of scientific institutes and pharmaceutical companies.
Sinan Ma   +10 more
doaj   +1 more source

Optimal Market Design [PDF]

open access: yesSSRN Electronic Journal, 2010
This paper introduces three methodological advances to study the optimal design of static and dynamic markets. First, we apply a mechanism design approach to characterize all incentive-compatible market equilibria. Second, we conduct a normative analysis, i.e. we evaluate alternative competition and innovation policies from a welfare perspective. Third,
Boone, Jan, Goeree, Jacob K
openaire   +6 more sources

Multi-objective topology design optimization combined with robust optimization

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2023
Topology optimization (TO), which is a design optimization technique that does not require design parameters, has been attracting attention. TO has a high degree of freedom and can obtain a novel design shape suitable for desired purposes.
Akito MARUO   +4 more
doaj   +1 more source

Optimal experimental design for optimal process design: A trilevel optimization formulation

open access: yesAIChE Journal, 2019
AbstractTypical optimal experimental design (OED) methods aim at minimizing the covariance matrix of the estimated parameters regardless of the intended application of the model that is being estimated. This can unnecessarily increase the experimental costs.
Walz, Olga   +2 more
openaire   +3 more sources

High-dimensional aerodynamic data modeling using a machine learning method based on a convolutional neural network

open access: yesAdvances in Aerodynamics, 2022
Modeling high-dimensional aerodynamic data presents a significant challenge in aero-loads prediction, aerodynamic shape optimization, flight control, and simulation.
Bo-Wen Zan   +4 more
doaj   +1 more source

A-optimal design matrices

open access: yesDiscrete Mathematics, 1984
The tools in search of A-optimal designs are listed and the authors derive A-optimal chemical balance weighing designs (that is, \(N\times n\) matrices with elements 1, -1 and 0) for \(N\geq 7\), \(n\leq 6\).
Chi Song Wong, Joseph C. Masaro
openaire   +1 more source

Learning-based ship design optimization approach

open access: yes, 2012
With the development of computer applications in ship design, optimization, as a powerful approach, has been widely used in the design and analysis process.
Philip Sayer   +5 more
core   +1 more source

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