Results 71 to 80 of about 2,311,595 (304)

Robustness of A-optimal designs

open access: yesLinear Algebra and its Applications, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Masaro, Joe, Wong, Chi Song
openaire   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti   +12 more
wiley   +1 more source

Efficient design optimization of complex electromagnetic systems using parametric macromodeling techniques [PDF]

open access: yes, 2011
We propose a new parametric macromodeling technique for complex electromagnetic systems described by scattering parameters, which are parameterized by multiple design variables such as layout or substrate feature.
Antonini, Giulio   +4 more
core   +2 more sources

Optimal design of robots

open access: yesRobotics: Science and Systems I, 2005
Synthesis of robots may be decomposed into two processes: {\em structural synthesis} (determine the general arrangement of the mechanical structure such as the type and number of joints and the way they will be connected) and {\em dimensional synthesis} (determine the length of the links, the axis and location of the joints, the necessary maximal joint
openaire   +2 more sources

Optimal Design of Cams

open access: yesMultibody System Dynamics, 2002
The paper presents a methodology which is based on a constrained optimization algorithm where the constraints are the maximum valve lift and timing. The objective is to maximize the time integral of valve area opened to gas flow. Once the optimal lift is known, the cam profile can be developed using inverse kinematic analysis. Finally, the authors give
Cardona, Alberto   +2 more
openaire   +3 more sources

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Development of Novel Nrf2/ARE Inducers Bearing Pyrazino[2,1-a]isoquinolin Scaffold with Potent In Vitro Efficacy and Enhanced Physicochemical Properties

open access: yesMolecules, 2017
Pyrazino[2,1-a]isoquinolin analogues were reported as potent activators of Nrf2/ARE signaling both in vitro and in vivo by our group. In this study, we simplified the ring system to investigate the functions of various parts of the pyrazino[2,1-a ...
Hongbin Dai   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Identification of Inhibitors of the Anti-Infective Target DXS Using Dynamic Combinatorial Chemistry

open access: yesProceedings, 2019
Antibiotic resistance is one of the biggest threats to humankind [1,2]. [...]
Ravindra P. Jumde   +3 more
doaj   +1 more source

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