Results 81 to 90 of about 17,265,464 (329)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Molecules, 2017 Pyrazino[2,1-a]isoquinolin analogues were reported as potent activators of Nrf2/ARE signaling both in vitro and in vivo by our group. In this study, we simplified the ring system to investigate the functions of various parts of the pyrazino[2,1-a ...
Hongbin Dai +4 more
doaj +1 more source
Concepts and methods in optimization of integrated LC VCOs [PDF]
, 2001 Underlying physical mechanisms controlling the noise properties of oscillators are studied. This treatment shows the importance of inductance selection for oscillator noise optimization. A design strategy centered around an inductance selection scheme is
Hajimiri, Ali, Ham, Donhee
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Machine Learning: Science and Technology, 2023 The Vlasov–Poisson equation is one of the most fundamental models in plasma physics. It has been widely used in areas such as confined plasmas in thermonuclear research and space plasmas in planetary magnetospheres.
Baiyi Zhang +5 more
doaj +1 more source
Joint Pilot Design and Uplink Power Allocation in Multi-Cell Massive MIMO Systems
, 2018 This paper considers pilot design to mitigate pilot contamination and provide good service for everyone in multi-cell Massive multiple input multiple output (MIMO) systems. Instead of modeling the pilot design as a combinatorial assignment problem, as in
Björnson, Emil +2 more
core +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Metals, 2020 In this work, we studied a Ti-Nb-Zr-Sn system for exploring novel composition and temperatures that will be helpful in maximizing the stability of β phase while minimizing the formation of α” and ω-phase. The Ti-Nb-Zr-Sn system is free of toxic elements.
Rajesh Jha, George S. Dulikravich
doaj +1 more source
Prediction and Optimization of the Design and Process Parameters of a Hybrid DED Product Using Artificial Intelligence [PDF]
, 2022 Metin Çallı +2 more
openalex +1 more source
An Experimental Evaluation of Bayesian Optimization on Bipedal Locomotion
, 2013 © 2014 IEEE.The design of gaits and corresponding control policies for bipedal walkers is a key challenge in robot locomotion. Even when a viable controller parametrization already exists, finding near-optimal parameters can be daunting.
Calandra, R +3 more
core +1 more source