Results 111 to 120 of about 31,965,129 (228)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Bibliometrics Analysis and Knowledge Mapping of Fragment-Based Drug Design Research: Trends from 2015 to 2024. [PDF]

Drug Des Devel Ther
He C, Zhang J, Zhang R, Liu L, Luo J, Zhang W, Fang B.   +6 more
europepmc   +1 more source

Researcher introspection for experience-driven design research

Design Studies, 2019
Haian Xue, P. Desmet
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Design research on a smart infusion device to reduce medical workload and enhance patient safety. [PDF]

Sci Rep
Mu B, Wang Y, Liu X, Bebit MP, Chen M, Wu H, Zhang W, Wang L, Fang Y, Dong K.   +9 more
europepmc   +1 more source

User Experience of the Co-design Research Approach in eHealth: Activity Analysis With the Course-of-Action Framework.

JMIR Hum Factors, 2022
Tremblay M, Hamel C, Viau-Guay A, Giroux D.   +3 more
europepmc   +1 more source

Rectus Femoris Mimicking Ultrasound Phantom for Muscle Mass Assessment: Design, Research, and Training Application. [PDF]

J Clin Med, 2021
Nakanishi N, Inoue S, Tsutsumi R, Akimoto Y, Ono Y, Kotani J, Sakaue H, Oto J.   +7 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Implementing IPE in a Workplace Setting: Educational Design Research Promotes Transformative Participation. [PDF]

Perspect Med Educ
Versluis MAC, Zöllner LS, Papadopoulou S, van der Stouwe R, de Haan-Gremme MC, Tsiamparlis-Wildeboer AHC, Helmholt H, de Carvalho-Filho MA.   +7 more
europepmc   +1 more source