Results 191 to 200 of about 61,817,433 (314)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The Design Rationale and Preliminary Evaluation of a Prototype Designed by People With Lived Experience of Psychosis and Professionals: Design Research Study. [PDF]

J Particip Med
Veldmeijer L, Terlouw G, Van 't Veer J, Van Os J, Boonstra N.   +4 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A Collaborative Communities-of-Practice Methodology for Environmental Design Research: A Case Study Application in Palliative Care. [PDF]

HERD
Jonescu EE, Farrell B, Ramanayaka CE, Delaney L, Litton E, Uylaki TJ, Watts G, Brigham B, Bellemore F, Seah D.   +9 more
europepmc   +1 more source

How might we motivate uptake of the Dual Prevention Pill? Findings from human-centered design research with potential end users, male partners, and healthcare providers. [PDF]

Front Reprod Health, 2023
Nyagah W, Segal K, Feltham J, Ash A, Major J, Masani M.   +5 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Sailing Into Uncharted Territory: Victim Survivors' Perspectives on Some of the Tensions of Engagement as Partners in Co-Design Research. [PDF]

Violence Against Women
Lamb K, Fiolet R, Broadhurst K, De Silva HS, Hegarty K.   +4 more
europepmc   +1 more source

Virtual Deliberate Practice Module for Tracheostomy Change Training: An Application of Educational Design Research. [PDF]

ATS Sch, 2022
Benjamin JC, Flores S, Jain P, Kumar S, Thammasitboon S.   +4 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Performance Optimization of Triangular Cantilever Beam Piezoelectric Energy Harvesters: Synergistic Design Research on Mass Block Structure Optimization and Negative Poisson's Ratio Substrate. [PDF]

Micromachines (Basel)
Ren R, Li B, Liu J, Zhang Y, Xu G, Liu W.   +5 more
europepmc   +1 more source