Results 191 to 200 of about 7,571,405 (316)

Sailing Into Uncharted Territory: Victim Survivors' Perspectives on Some of the Tensions of Engagement as Partners in Co-Design Research. [PDF]

Violence Against Women
Lamb K, Fiolet R, Broadhurst K, De Silva HS, Hegarty K.   +4 more
europepmc   +1 more source

Ageing well with diabetes: A workshop to co-design research recommendations for improving the diabetes care of older people. [PDF]

Diabet Med, 2022
Wylie TAF, Morris A, Robertson E, Middleton A, Newbert C, Andersen B, Maltese G, Stocker R, Weightman A, Sinclair A, Bain SC.   +10 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Performance Optimization of Triangular Cantilever Beam Piezoelectric Energy Harvesters: Synergistic Design Research on Mass Block Structure Optimization and Negative Poisson's Ratio Substrate. [PDF]

Micromachines (Basel)
Ren R, Li B, Liu J, Zhang Y, Xu G, Liu W.   +5 more
europepmc   +1 more source

Common Shortcomings in Study on Radiopharmaceutical Design Research: A Case Study of ^99mTc-Labelled Methotrexate. [PDF]

Molecules, 2021
Koźmiński P, Halik PK, Chesori R, Gniazdowska E.   +3 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Molecular biology and design research : A new paradigm and transdisciplinary approach to communicating science. [PDF]

EMBO Rep
Molins-Pitarch C, Krebs J, Brena D.
europepmc   +1 more source

Educational design research: Portraying, conducting, and enhancing productive scholarship. [PDF]

Med Educ, 2021
McKenney S, Reeves TC.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Action design research to develop an interactive dashboard to visualise and compare patient data from Irish general practice (CARA). [PDF]

BMJ Open
Vornhagen H, Garzón-Orjuela N, Stasiewicz K, Garcia Pereira A, Parveen S, Porwol L, Collins C, Blake C, Vellinga A.   +8 more
europepmc   +1 more source