Results 101 to 110 of about 5,060,080 (299)
The optimal design of standard gearsets [PDF]
, 1983 A design procedure for sizing standard involute spur gearsets is presented. The procedure is applied to find the optimal design for two examples - an external gear mesh with a ratio of 5:1 and an internal gear mesh with a ratio of 5:1.
Coy, J. J., Savage, M., Townsend, D. P.
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Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Designing Guiding Systems for Brain-Computer Interfaces
Frontiers in Human Neuroscience, 2017 Brain–Computer Interface (BCI) community has focused the majority of its research efforts on signal processing and machine learning, mostly neglecting the human in the loop.
Nataliya Kosmyna, Anatole Lécuyer
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Design concepts for bioreactors in space [PDF]
Microbial food sources are becoming viable and more efficient alternatives to conventional food sources especially in the context of Closed Ecological Life Support Systems (CELSS) in space habitats. Since bioreactor designs for terrestrial operation will
Beard, B. +3 more
core +1 more source
Optimization of Discrete-parameter Multiprocessor Systems using a Novel Ergodic Interpolation Technique [PDF]
, 2015 Modern multi-core systems have a large number of design parameters, most of which are discrete-valued, and this number is likely to keep increasing as chip complexity rises. Further, the accurate evaluation of a potential design choice is computationally
Desai, Madhav P., Karanjkar, Neha V.
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
LIBERACIÓN DE LOTES PARA PRODUCTOS EN DESARROLLO/ BATCH RELEASE FOR INVESTIGATIONAL PRODUCTS
Revista Científica de Ingeniería Industrial, 2012 Este artículo describe un procedimiento de liberación de productos en desarrollo del Centro de Inmunología Molecular. El Procedimiento incorpora el conocimiento y la complejidad de la investigación y desarrollo (I+D), análisis de riesgo, correlaciones y ...
Daymara González-Fuentes +3 more
doaj
On the two-phase framework for joint model and design-based inference [PDF]
We establish a mathematical framework that formally validates the two-phase “superpopulation viewpoint” proposed by Hartley and Sielken (1975), by defining a product probability space which includes both the design space and the model space. We develop a
Ioana Schiopu Kratina +1 more
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