Results 111 to 120 of about 361,254 (315)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2020 Caravana Mexicanas del Futuro, Trazando Conciencias Pensando en TI: Alcaldía Álvaro Obregón. 18 de enero 2020, 10:00 - 18:00; agenda: Sesión inaugural -participan Marina Vicario (RedLaTE), Francisco Ramírez (CELAMEX), José Luis Ponce López (ANUIES ...
Gertrudiz, Nancy
core
Components of Design Thinking in Spatial Design Education and a Model Proposal
Iconarp International Journal of Architecture and PlanningDesign thinking, defined in its simplest form as a creative problem-solving process, is interpreted in various ways in the literature, with differing models and components.
ipek yıldırım coruk
doaj +1 more source
Application of the design strategy that is supported by lateral thinking techniques in product design [PDF]
Journal of Architecture, Art & Humanistic ScienceLateral thinking methods have a key role in developing the designer's ability to deal with challenges and life situations in a more creative way. It gives him the power to produce original and unique ideas.
Ahmed Kassab, Sayed Abdou Ahmed Abdou
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Applying Design Thinking Elsewhere: Organizational context matters [PDF]
, 2014 In this contribution design thinking is taken as a transfer of design methods from product development to other domains. It is argued that the success of this transfer depends on the organisational context offered to design thinking in these other ...
Smulders, F.E.H.M. +5 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Política e Gestão Educacional: Este estudo investiga como os projetos STEM estruturados pelo design thinking aprimoram simultaneamente as competências de alfabetização científica alinhadas ao PISA-2025 e do Sustainability Awareness Framework (SusAF) em futuros professores de ...
Halim Simatupang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source