Results 111 to 120 of about 2,162,136 (285)
The Butterfly Effect: Creative Sustainable Design Solutions through Systems thinking [PDF]
, 2007 FAIM: Intelligent Manufacturing now, Limerick ...
Hadfield, Mark, McMahon, M.
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Giving voice to equitable collaboration in participatory design [PDF]
, 2007 An AHRC funded research project titled Experimenting with the Co-experience Environment (June 2005 – June 2006) culminated in a physical environment designed in resonance with a small group of participants.
Ivey, Marlene +6 more
core +1 more source
Critical-Thinking Skills of First-Year Athletic Training Students Enrolled in Professional Programs
, 2017 Context: The Examination of Professional Degree Level document presented to the National Athletic Trainers’ Association Board of Directors states that research in athletic training education has not investigated differences in the critical-thinking ...
Bates, Dana K.
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
First make something – principled, creative design as a tool for multi-disciplinary research in clinical engineering [PDF]
, 1999 Design provides a set of tools for exploring our world and these can give very different insights from the tools of the natural scientist or social scientist.
Rust, C., Whiteley, G., Wilson, A.
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Enhancing Creativity in Interaction Design: Alternative Design Brief [PDF]
, 2008 This paper offers a critique of the design brief as it is currently used in teaching interaction design and proposes an alternative way of developing it.
Dix, Alan, Sas, Corina
core
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source