Results 111 to 120 of about 359,417 (313)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Política e Gestão Educacional: Este estudo investiga como os projetos STEM estruturados pelo design thinking aprimoram simultaneamente as competências de alfabetização científica alinhadas ao PISA-2025 e do Sustainability Awareness Framework (SusAF) em futuros professores de ...
Halim Simatupang +4 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Design Thinking and Participation: Lessons Learned from Three Case Studies [PDF]
This paper examines how design thinking and serious games approaches can be used to support participation through the analysis of three case studies. Indeed we will analyze these approaches in three different contexts: (i) a state-owned multi-utilities ...
Olivier Glassey +3 more
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Design Thinking Applied: The Process of Creating a Technology-Mediated Debriefing Module [PDF]
, 2018 This qualitative case study explored the effectiveness of using design thinking to create a technology-mediated debriefing module (mock up/story board) for practical nursing students.
Taberner, Christy
core
, 2022 LAUREA MAGISTRALEIl design thinking ha dimostrato più volte la sua efficacia in tutti i settori. Ha permesso di innovare prodotti, servizi e sistemi. Tuttavia, i designer sono spesso messi in difficoltà da controparti non designer quando implementano ...
Dubus, Elisabeth
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
The educational design ladder : creation of a multi-discipline design thinking program
, 2014 As global industries change and technology advances, traditional education systems may no longer be able to supply companies with graduates possessing an appropriate mix of skills and experience.
Wrigley, Cara, Straker, Karla
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Where Does Design Thinking Leave Design? Snapshots of a Conversation with the Design Community.
, 2020 Design Thinking has gained recognition as an acclaimed process for generating innovative, human centred solutions at a social and business level. It has also gained notoriety amongst many designers, who claim that its success as an exported element of ...
Douglas, Michelle +3 more
core +1 more source