Results 91 to 100 of about 10,786,537 (257)

Implementing Design Thinking: understanding organizational conditions [PDF]

open access: yes, 2023
The advent of design thinking as a tool for innovation has led to its adoption in a range of organizations. While proponents of design thinking continue to focus on the principles and practices of their method, little is known on the organizational ...
Wrigley, Cara   +2 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Why migration studies should use design thinking? [PDF]

open access: yes
design thinking! Design thinking is a creative approach which brings people from all walks of life together, helps them understand each other’s realities, and co-create new, practical solutions that work for those impacted the most. In this short,
BISSINGER, Jutta   +2 more
core   +1 more source

DEEP EMPATHIC DESIGN

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
Empathic design is often described as a creative process that translates observations - typically of people and their behaviours into design ideas.
FRAQUELLI Roberto
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Regulation or deregulation: a reflection from the perspective of design thinking

open access: yes, 2020
El design thinking, como proceso y metodología, se centra en el usuario. Es una propuesta de proceso libre pero sistemático de gestión de la creatividad para la innovación en cinco etapas.
Méndez Reátegui, Rubén Carlos Braulio   +1 more
core   +1 more source

Design Thinking: A Rod for Design’s Own Back? [PDF]

open access: yes, 2016
Design Thinking is frequently argued to be unlike scientific thinking. Existing literature questions the validity of this differentiation with regards to: the characterisation of scientific thinking in design research; the notion that designers are more ...
Aysar Ghassan, Ghassan, Aysar
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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