Results 81 to 90 of about 359,417 (313)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Design thinking pedagogy: The educational design ladder
, 2015 As global industries change and technology advances, traditional education systems might no longer be able to supply companies with graduates who possess an appropriate mix of skills and experience.
Wrigley, Cara, Straker, Karla
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Design-Thinking-Diskurse Bestimmung, Themen, Entwicklungen
, 2014 Der Untersuchungsgegenstand der vorliegenden Arbeit ist, die mit dem Begriff "Design Thinking" verbundenen Diskurse zu bestimmen und deren Themen, Konzepte und Bezüge herauszuarbeiten.
Lindberg, Tilmann Sören
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Sustainable Silica‐Carbon Nanofiber Hybrid Composite Anodes for Lithium‐Ion Batteries
Macromolecular Materials and EngineeringAlternative anode materials with increased theoretical specific capacities are under scrutinity as a replacement to graphite in lithium‐ion batteries (LiBs).
Anne Beaucamp +6 more
doaj +1 more source
, 2020 The term design thinking has gained considerable attention over the past decade in a wide range of organizations and contexts beyond the traditional preoccupations of designers.
Kimball, Lucy
core
The design thinking approaches of three different groups of designers based on self-reports [PDF]
, 2013 This paper compares the design thinking approaches of three groups of student-designers: industrial design and architecture undergraduates, and design PhD candidates. Participants responded to an open-ended design brief, working individually.
Goldschmidt, Gabriela +3 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source