Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
PERANCANGAN UI/UX SISTEM MONITORING DAN EVALUASI MUSRENBANG MENGGUNAKAN METODE DESIGN THINKING (Studi Kasus Bappeda Kabupaten Malang) [PDF]
This study focuses on the design of a UI/UX monitoring and evaluation system for the Musrenbang using the Design Thinking method, specifically for the Bappeda of Malang Regency.
Khuluq, Mohamad Farid Wafi Husnul
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Identifikasi Penerapan Design Thinking dalam Pembelajaran Perancangan Desain Interior Kantor [PDF]
, 2018 Design Thinking sebagai pola berpikir kreatif diterapkan dalam pembelajaran perancangan desain interior maupun arsitektur. Program studi desain interior Universitas Kristen Petra juga menerapkan proses ini dalam pembelajarannya dengan lima tahapan yaitu ...
Dewi, S. K. (Savitri ) +2 more
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Identifying waste in virtual design and construction practice from a Lean Thinking perspective: A meta-analysis of the literature [PDF]
, 2016 María Guadalupe Mandujano Rodríguez +3 more
openalex +1 more source
Perancangan Aplikasi SOL-MATH Untuk Pendidikan Matematika SMP/Sederajat dengan Metode Design Thinking [PDF]
, 2022 Arsyillah Majid +2 more
openalex +1 more source
Design-Led Thinking for Improving Public Policy Performance [PDF]
, 2016 Introduction “Design is a funny word. Some people think design means how it looks. But of course, if you dig deeper, it\u27s really how it works,” said Steve Jobs in 1996.1 Design is an essential element of all public services.
Bholey, M. (Mihir)
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Value innovation modelling: Design thinking as a tool for business analysis and strategy [PDF]
, 2010 This paper explores the use of multiple perspective problem framing (English 2008) as a tool to reveal hidden value and commercial opportunity for business.
English, Stuart +2 more
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source