Results 131 to 140 of about 2,154,958 (312)
‘Bag for Life’ – using multidisciplinary approaches in design pedagogy to develop global citizenship [PDF]
, 2010 As the need to integrate approaches to sustainable thinking and global citizenship becomes ever more pressing, a multi disciplinary project has been initiated at Northumbria University's School of Design to address these issues.
Ghassan, Aysar, Rowe, Gill
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Does design education always produce designers?
, 2011 By questioning what we mean by the term ‘designer’ this paper describes the ideas behind a new Open University course in Design Thinking. The paper shows how the creative skills of students can be consciously developed, and deliberately applied outside ...
Lloyd, Peter
core
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
FADE-CTP: A Framework for the Analysis and Design of Educational Computational Thinking Problems [PDF]
Giorgia Adorni +7 more
openalex +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Exploring Career and Life Design: Innovation, Resilience, and Personal Growth
CERN IdeaSquare Journal of Experimental InnovationIn the scientific spirit of CERN, this Special Issue focuses on humanity's biggest experiment: Life Design. It is about transformations and innovations related to the most profound questions of what it means to design your life in your personal and ...
Bettina Maisch +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
DESIGN INSTRUCIONAL ERGONÔMICO E DESIGN THINKING [PDF]
, 2017 Crislaine Gruber +2 more
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source