Designer Drug Detective Work [PDF]
ACS Central Science, 2016 O n an unseasonably warm spring morning in his office in Baltimore, neurochemist Michael H. Baumann eagerly flipped through a spreadsheet. It listed hundreds of chemical names of suspected drugs seized by local, state, and federal law enforcement ...
Erika Gebel Berg
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Identification and characterization of new designer drug 4-fluoro-PV9 and α-PHP in the seized materials. [PDF]
Forensic Toxicol, 2016 In this study, we present identification and physicochemical characterization of new cathinone derivatives, 4-fluoro-PV9 and already known α-PHP in seized materials.
Majchrzak M +4 more
europepmc +4 more sources
Disrupting the medial prefrontal cortex with designer receptors exclusively activated by designer drug alters hippocampal sharp-wave ripples and their associated cognitive processes. [PDF]
Hippocampus, 2021 The hippocampus and medial prefrontal cortex (mPFC) interact during a myriad of cognitive processes including decision‐making and long‐term memory consolidation.
Schmidt B, Redish AD.
europepmc +2 more sources
Central Effects of the Designer Drug Mephedrone in Mice—Basic Studies [PDF]
Brain Sciences, 2022 Mephedrone belongs to the “party drugs” thanks to its psychostimulant effects, similar to the ones observed after amphetamines. Though mephedrone is used worldwide by humans and in laboratory animals, not all properties of this drug have been discovered ...
Anna Serefko +7 more
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Hallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats. [PDF]
Neurotox Res, 2019 NBOMes are N-benzylmethoxy derivatives of the 2C family hallucinogens. 4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine (25I-NBOMe) is one of the commonly used illicit drugs.
Herian M +5 more
europepmc +2 more sources
An In Vitro Study of the Neurotoxic Effects of N-Benzylpiperazine: A Designer Drug of Abuse. [PDF]
Neurotox Res, 2016 Recently, the number of new psychoactive substances has significantly increased. Despite the systematic introduction of prohibition in trade of medicinal products which mimic the effects of illegal drugs, the problem concerning this group of drugs is ...
Persona K +5 more
europepmc +2 more sources
Identificação química da clorofenilpiperazina (CPP) em comprimidos apreendidos Chemical identification of chlorophenylpiperazine in seized tablets [PDF]
Química Nova, 2010 Designer drug is a term used to describe psychoactive drugs of abuse which are usually synthesized by modifying the molecular structures of existing drugs of abuse.
Rafael Lanaro +3 more
doaj +4 more sources
Cannabidiol-Derived Cannabinoids: The Unregulated Designer Drug Market Following the 2018 Farm Bill [PDF]
Medical Cannabis and CannabinoidsBackground: In this review, we summarize current scientific knowledge on psychoactive cannabinoids synthesized from cannabidiol (CBD) and sold in the semi-legal market established in response to the passage of the US Agriculture Improvement Act of 2018 ...
Charles N. Zawatsky +4 more
doaj +2 more sources
Optimized pipeline and designer cells for synthetic-biology-based high-throughput screening of viral protease inhibitors [PDF]
Cell Reports: MethodsSummary: A reliable, efficient, high-throughput pipeline to evaluate viral protease inhibitors would enhance antiviral drug discovery. Methods such as crystallography and phenotypic screening are often constrained by complex assay conditions, limited ...
Shlomi Edri +10 more
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The Psychoactive Designer Drug and Bath Salt Constituent MDPV Causes Widespread Disruption of Brain Functional Connectivity. [PDF]
Neuropsychopharmacology, 2016 Colon-Perez LM +9 more
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