Results 81 to 90 of about 1,273,827 (295)

Obowiązek naprawienia szkody wyrządzonej użyciem środków zastępczych jako przykład możliwej reakcji prawa cywilnego na obrót tak zwanymi dopalaczami

Acta Iuris Stetinensis, 2018
The basic function of civil law, and more broadly private law is the regulation of legal relations between legal entities deciding on their effective creation, change or termination.
Szymon Słotwiński
doaj   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Apparent dissociation between hemodynamic and neurochemical responses during chemogenetic modulation of cortical circuits in rats

Frontiers in Neuroscience
IntroductionChemogenetic tools such as Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) provide a powerful means to causally manipulate defined neuronal populations in vivo.
Fatemeh Anvari-Vind, Nathalie Just, Nathalie Just   +2 more
doaj   +1 more source

The analysis of admissions to the Emergency Department of the Psychiatric Hospital in Bielsko-Biała connected with psychotic disorders induced by psychoactive drug use

Psychiatria i Psychologia Kliniczna, 2018
Background: The recreational use of psychoactive substances has become quite popular nowadays, yet there a sufficient body of data about psychotic disorders associated with toxicity of these substances is still lacking.
Magdalena Joanna Kaizer-Będkowska, Krzysztof Artur Kucia   +1 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

‘Designer drugs’ being sold as ‘bath salts’ and ‘spice’ causing concern.

, 2013
NEW DRUGS MARKETED as “legal highs” and “designer drugs” are emerging fast and in great numbers, and authorities are struggling to keep up, a new UN report warned today. So-called new psychoactive substances (NPS), often sold under harmless names like

core  

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Early Warning - A Pilot Study of Designer Drugs in Tables for Illicit Sale in Denmark

, 2001
Early Warning,Designer drugs,Illicit sale,East ...
Müller, Irene Breum, Nielsen, Erik
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source