Results 101 to 110 of about 16,330 (302)
Cross-reactivities of 41 new amphetamine designer drugs to EMIT® immunoassays [PDF]
, 2013 Amphetamine designer drugs are central nervous system stimulants, and are widely diffused in illegal markets. Monitoring of drugs of abuse in biological fluids is successfully used for clinical and forensic applications.
BOATTO, Gianpiero +4 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Correction to: Pharmacological affinity fingerprints derived from bioactivity data for the identification of designer drugs. [PDF]
J Cheminform, 2022 He K.
europepmc +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Role of Forensic Chemistry and Analytical Intrumentation in the Identification of Designer Drugs [PDF]
, 2021 This thesis describes the overall issues that designer drugs are causing in society today. There are three main types of structural differences between designer drugs and the parent drug they are created from.
Barko, Mariah A
core +1 more source
Rapid Targeted Method of Detecting Abused Piperazine Designer Drugs. [PDF]
J Clin Med, 2021 Welz A +3 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Designer drugs : analytical and biological aspects [PDF]
, 2012 In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and ...
Bulcão, Rachel Picada +7 more
core
Pharmacological affinity fingerprints derived from bioactivity data for the identification of designer drugs. [PDF]
J Cheminform, 2022 He K.
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source