Results 111 to 120 of about 93,845 (280)

Cardiotoxicity of new psychoactive substances – A review of experimental studies and real clinical and forensic cases

Annales Academiae Medicae Silesiensis
Designer drugs pose a serious modern health threat, specially the two most popular groups: synthetic cannabinoids and synthetic cathinones. Most of the available literature focuses on the neurological effects and scarcely describes effects on the ...
Rafał Skowronek, Alexander Suchodolski
doaj   +1 more source

Mind Your Meds: Safe Opioid Disposal Awareness [PDF]

, 2019
Driven by the effects of the opioid epidemic on friends, family members, students, and patients, members of the 2019 GEHLI Team “Mission Possible” are dedicated to bolstering educational awareness of safe leftover opioid disposal methods to decrease the ...
at Virginia Commonwealth University, The Grace E. Harris Leadership Institute, Davies, Mary Ann, Fox, Jenny, Johnson, Kenneth, Papenfuse, Jennifer, Schmitt, Michelle, Zhang, Shijun, Zoghby, Lori   +7 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Designer Receptors Exclusively Activated by Designer Drugs Approach to Treatment of Sleep-disordered Breathing. [PDF]

Am J Respir Crit Care Med, 2021
Fleury Curado T, Pho H, Freire C, Amorim MR, Bonaventura J, Kim LJ, Lee R, Cabassa ME, Streeter SR, Branco LG, Sennes LU, Fishbein K, Spencer RG, Schwartz AR, Brennick MJ, Michaelides M, Fuller DD, Polotsky VY.   +17 more
europepmc   +1 more source

Knowledge, attitudes, and practices of Chinese college students towards novel psychoactive substances

BMC Public Health
Background This study aimed to investigate the knowledge, attitudes, and practices (KAP) among Chinese college students regarding novel psychoactive substances (NPS), where practices specifically refer to behaviors related to NPS access and usage ...
Liqin Lu, Xinhao Zhou, Jue Deng, Binling Zhu, Liang Meng, Xianghui Lai, Xiaoli Zhu   +6 more
doaj   +1 more source

The major changes in medical practice in the 20th century [PDF]

, 2000
One could truly say that there were more advances in medicine in the last 60 years than there had been in the previous 500 years. Indeed the medical breakthroughs of the last 50 years have probably saved more lives than those of any epoch since medicine ...
Fenech, Frederick F.
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Filter Feature Selection for Unsupervised Clustering of Designer Drugs Using DFT Simulated IR Spectra Data. [PDF]

ACS Omega, 2021
He K.
europepmc   +1 more source

Determinant criteria for designing Health benefit package in selected countries [PDF]

, 2013
Health benefit package described as primary health interventions that provided with government using general funds for all regardless their financial ability.
Behnampour, N., Delgoshaei, B., Etemad, K., Heidari, A., Jafari, N., Javad Kabir, M., Ravaghei, H., Reza Honarvar, M., Vatankhah, S.   +8 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source