Results 91 to 100 of about 1,273,827 (295)

Designer drugs: spice and bath salts

open access: yes, 2016
Discusses the dangers of designer drugs, including the target audience and marketing and purchasing of the ...
Koukel, Sonja;
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Designer-Material Relationship Model

open access: yes, 2023
This model represents the relationship between the designer and their materials in an upcycling design process, specifically related to upcycling quilt materials.
Colleen Pokorny (16413429)
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Drug Design and Drug Discovery

open access: yesInternational Journal of Innovative Science and Research Technology (IJISRT)
One of the key forces influencing the advancement of pharmaceuticals, biotechnology, and pharmacology is the drug industry. The process of finding and creating medications is known as drug discovery. It is a procedure designed to find a substance that has therapeutic value in treating and curing illness.
Aditya Maurya   +4 more
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Psychological disorders related to designer drugs

open access: yes, 2000
Examines the history, nature, effects, and dangers of such designer drugs as Ecstasy, PCP, fentanyl, and ...
Connelly, Elizabeth Russell
core  

Cross-reactivity of commercial immunoassays for screening of new amphetamine designer drugs. A review

open access: yes, 2022
: The chemical modification of the molecular structure of psychoactive substances is a very common practice in the illicit drugs market, to by-pass current regulations; this lead to the production of compounds, known as "designer drugs", with the same or
Baralla, Elena   +9 more
core   +1 more source

Case Report: Mislabeling of an online “alprazolam triazolobenzophenone” pill leads to severe intoxication with the novel synthetic opioid cychlorphine

open access: yesFrontiers in Toxicology
BackgroundMislabeling of illicit drug products poses a serious risk to public health, especially in the rapidly evolving market for new psychoactive substances (NPS). Products sold as benzodiazepines may contain undisclosed novel synthetic opioids (NSOs),
Annette Zschiesche   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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