Results 71 to 80 of about 390,801 (245)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Hamlet e o problema da verdade

open access: yesPsicologia: Teoria e Pesquisa
Este artigo discute o problema da verdade, a partir da obra Hamlet e da produção teórica da Psicanálise. Objetiva mostrar a centralidade de tal problema, tanto no teatro quanto no processo analítico, e explorar alguns de seus aspectos tais como a ...
Maria Thereza Ávila Dantas Coelho
doaj   +1 more source

W fabryce pragnienia. Gillesa Deleuze'a i Felixa Guattariego teoria nieświadomego [The Factory of Desire. Gilles Deleuze and Felix Guattari's Theory of the Unconscious] [PDF]

open access: yesAnaliza i Egzystencja, 2012
The text presents the theory of the unconscious that can be found in the worksof the philosophico-psychoanalytical pair of French thinkers: Gilles Deleuzeand Felix Guattari. Their theory was conceived in opposition to the classicalfreudian psychoanalysis
Krzysztof Skonieczny
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Lo que interpela en la pareja. Tres momentos de la no-proporción sexual.

open access: yesAffectio Societatis, 2015
In this article we will study three moments of Lacan's teaching in order to locate the place of the loving partner when he cannot be reduced to the condition of counterpart.
Luciano Lutereau, Santiago Thompson
doaj  

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Del deseo en las mujeres. Respuestas de las mujeres frente a la falta.

open access: yesAffectio Societatis, 2015
This paper aims to present the findings of the research called “On Desire in Women” and to explain the method used and the investigative pathway that took place which was carried out from Freud's theory and Lacan's teaching.
Olga Lucia Naranjo Osorio
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

La Antigona de Lacan. Comentario al apartado "La esencia de la tragedia" del seminario 7, la ética del psicoanálisis. // Lacan`s Antigone: a commentary on the section titled "The essence of tragedy" on seminar 7, the ethics of psychoanalysis.

open access: yesAffectio Societatis, 2010
The purpose of the present paper is to show the most important elements in Lacan´s presentation related to the section titled The Essence of Tragedy in his seminar The Ethics of Psychoanalysis, by extracting from it the nodal aspects between ethics and ...
Jorge Iván Jaramillo.
doaj  

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