Results 111 to 120 of about 18,110 (202)

Vimentin Intermediate Filaments: A Paradigm Shift From Static Structure to Dynamic Cytoplasmic Network

BioEssays, Volume 48, Issue 3, March 2026.
Vimentin intermediate filaments form a dynamic, motile network that interacts with microfilaments and microtubules. We propose a hybrid transport model to explain vimentin filament dynamics through cytoskeletal crosstalk and organelle‐associated transport.
Bhuvanasundar Renganathan, Stephen A. Adam, Vladimir I. Gelfand   +2 more
wiley   +1 more source

Breast Fibromatosis in a Patient With a History of Treated Breast Cancer: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Desmoid tumors are benign mesenchymal neoplasms that originate from muscular fasciae and aponeuroses. Breast involvement is exceptionally rare, accounting for less than 0.2% of all breast tumors. A 41‐year‐old woman with a history of right‐sided invasive ductal carcinoma (IDC) diagnosed in 2022 underwent breast‐conserving surgery (BCS) and ...
Saba Ebrahimian, Sakineh Soleimani Varaki, Faezeh Zabihi   +2 more
wiley   +1 more source

Epithelioid Sarcoma of the Forearm in a 70‐Year‐Old Woman: A Case Report at a Referral Facility in Tanzania

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Epithelioid sarcoma, though typically seen in young males, can occur in elderly patients and mimic benign lesions. Clinicians should maintain a high index of suspicion for chronic, slow‐growing extremity masses as accurate histopathological and immunohistochemical evaluation with complete surgical excision is crucial for optimal outcomes.
Furaha E. Kasyupa, Jeremia J. Pyuza, Abitalis Mayengela, Agumbwike Mwakitwange, Deardiana Sengelela, Gilbert Nkya, Patrick Amsi, Angela Pallangyo, Alex Mremi   +8 more
wiley   +1 more source

First Case of Neuroblastoma‐Like Somatic‐Type Malignancy Arising in the Teratomatous Component of a Mixed Non‐Seminomatous Testicular Germ Cell Tumor in an Adult

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Somatic malignant transformation (SMT) in germ cell tumors (GCTs) is a rare but clinically significant event. Among non‐seminomatous germ cell tumors (NSGCTs), teratomas can undergo malignant transformation, with neuroblastoma‐like differentiation being exceptionally rare.
Karl Ziade, Jana Kotaich, Serge Assaf, Valerie Aftimos, Adib Ziade   +4 more
wiley   +1 more source

Desmin [PDF]

, 2017
S. Holdenrieder, P. Stieber
openaire   +1 more source

Case Report: Parapharyngeal Leiomyosarcoma Mimicking Neurofibroma

Clinical Case Reports, Volume 14, Issue 3, March 2026.
Neurofibroma and leiomyosarcomas are rare tumors of the head and neck with similar imaging characteristics of T2 hyperintensity on MRI that can present with neurological deficits. However, leiomyosarcomas are malignant, and early diagnosis is critical to improved survival. Immunohistochemistry is crucial for assigning line of differentiation in spindle
Carson Brantley, Claudia N. Gutierrez, Sara Zadeh, Eric Dowling   +3 more
wiley   +1 more source

Orphan disease: features of difficult to diagnose and genetically verified muscular dystrophy based on DNA sequencing results (clinical case)

Acta Biomedica Scientifica
Currently, orphan diseases are rarely diagnosed due to low patient awareness, heterogeneity of symptoms, low publication activity of specialists who may encounter orphan pathology, and limited availability of molecular genetic technologies for verifying ...
Yu. I. Kotsenko
doaj   +1 more source

Vincristine‐Induced Unilateral Foot Drop in a Patient With Diffuse Large B‐Cell Lymphoma: A Rare Presentation of Severe Motor Axonopathy

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Vincristine is a cornerstone chemotherapeutic agent in combination regimens for lymphoid malignancies; however, its neurotoxicity remains a major dose‐limiting adverse effect. While vincristine‐induced peripheral neuropathy (VIPN) commonly presents as a symmetric, sensory‐predominant polyneuropathy, isolated unilateral motor neuropathy causing
Nishchal Regmi, Prashant Pant, Umang Gupta, Mipsang Lama   +3 more
wiley   +1 more source

Desmin-p.L112Q Disturbs Filament Formation and Is a Likely-Pathogenic Variant Associated with Dilated Cardiomyopathy

Journal of Cardiovascular Development and Disease
DES encodes the muscle-specific intermediate filament protein desmin, which is highly relevant to the structural integrity of cardiomyocytes. Mutations in this gene cause different cardiomyopathies including dilated cardiomyopathy.
Alexander Lütkemeyer, Sabrina Voß, Jonas Reckmann, Joline Groß, Anna Gärtner, Jan Gummert, Hendrik Milting, Andreas Brodehl   +7 more
doaj   +1 more source

Expanding the Anatomical Distribution of PRRX1::KMT2D Fusion Mesenchymal Neoplasms: A Rare Mediastinal Case Report

Cancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background PRRX1‐rearranged mesenchymal neoplasms are rare soft tissue tumors with a predilection for the superficial subcutaneous tissue. The PRRX1::KMT2D fusion variant is exceptionally rare, with only three previously reported cases, all of which were located in the intermuscular regions.
Weixiang Zhong, Yu Deng, Ke Sun
wiley   +1 more source