Results 91 to 100 of about 35,458 (213)
British Journal of Pharmacology, Volume 183, Issue 18, Page 5476-5495, September 2026.Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth +14 more
wiley +1 more source
BiomedicinesBackground/Objectives: Chronic kidney disease (CKD) is a progressive pathological condition which results in the severe fibrosis of the kidneys. However, the mechanisms of CKD progression and fibrogenesis remain unclear.
Andrija Vukovic +11 more
doaj +1 more source
What's Your Diagnosis? Large Mediastinal Mass in a Dog
Veterinary Clinical Pathology, EarlyView.
Rosane O. Cruz +7 more
wiley +1 more source
Intramuscular myxoma with chondroid features: two cases expanding the morphological spectrum
Histopathology, Volume 89, Issue 3, Page 554-557, September 2026.Background Intramuscular myxoma is a benign mesenchymal tumour typically composed of bland spindle to stellate cells in abundant myxoid stroma and usually characterized by GNAS mutations. Chondroid matrix has not been previously reported in intramuscular myxoma.
Bethany Batson +5 more
wiley +1 more source
What Is Your Diagnosis? Multiple Subcutaneous Lumps in a Horse
Veterinary Clinical Pathology, EarlyView.
Federica Meistro +4 more
wiley +1 more source
Development of the abdominal musculature in the chicken embryo
Journal of Anatomy, Volume 249, Issue 3, Page 618-633, September 2026.In this study, we investigate anatomy, morphogenesis, segmental origin, and fiber formation of the abdominal musculature in the chicken embryo. We show that abdominal muscles arise from somites 24 to 28, and that the segmental identity of individual fibers in the abdominal muscle sheets is maintained.
Margarethe Draga +6 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 15, 15 August 2026.Systolic overload increases the synthesis of cardiac proteins, both misfolded and native, leading to cardiac hypertrophy and elevated proteostasis burden. Meanwhile, systolic overload also increases Ser14‐RPN6 phosphorylation (pS14‐RPN6), thereby increasing proteasome (Psm) proteolytic capacity and meeting the increased demand for protein degradation ...
Md. Salim Ahammed +7 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1807-1813, August 2026.ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg +9 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi +5 more
wiley +1 more source