Results 91 to 100 of about 43,204 (229)
Desmin-related cardiomyopathy: an unfolding story
, 2011 The intermediate filament protein desmin is an integral component of the cardiomyocyte and serves to maintain the overall structure and cytoskeletal organization within striated muscle cells.
Jeffrey Robbins, Patrick M. McLendon
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Novel and emerging cutaneous soft tissue tumours
Histopathology, EarlyView.This review outlines the defining histopathological, immunophenotypic and molecular features of novel and emerging cutaneous soft tissue tumours, including hybrid superficial ALK‐rearranged myxoid spindle cell neoplasm/epithelioid fibrous histiocytoma, superficial neurocristic tumour, ALK‐rearranged epithelioid vascular neoplasm and MITF pathway ...
Saba Shafi, Josephine K Dermawan
wiley +1 more source
Malignant MITF-Rearranged PEComa With Novel EEF1A1::MITF Fusion. [PDF]
Genes Chromosomes CancerABSTRACT MITF‐rearranged PEComas are rare, and their relationship to MITF‐altered melanocytic tumors remains incompletely characterized. We report a malignant superficial soft tissue neoplasm of the thigh in a 45‐year‐old woman harboring a novel EEF1A1::MITF fusion. The tumor was composed of epithelioid to plump spindle cells arranged in sheets, nests,
Raney S +9 more
europepmc +2 more sources
The role of desmin in a heart [PDF]
, 2018 Desmin forms a muscle specific intermediate filament which participates in a formation of a dynamic intracellular network that links contractile apparatus with a sarcolemma, mitochondria and it provides a communication with a cell nucleus.
Šeovićová, Maja
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Histological manifestations of vitamin A toxicity in the liver
Histopathology, EarlyView.Analysing clinicopathological data from 1960 to 2025, this study characterizes the spectrum of liver injury associated with chronic vitamin A toxicity. Hepatic stellate cell hypertrophy/hyperplasia and sinusoidal fibrosis emerge as the predominant features, providing a morphological basis for diagnosing vitamin A hepatotoxicity.
Giorgio Cazzaniga +2 more
wiley +1 more source
Effects of mono ADP ribosylation on desmin assembly disassembly [PDF]
, 1998 Desmin, a muscle-specific intermediate filament protein, has previously been shown to be a substrate for endogenous mono-ADP-ribosyltransferase. In this work, the effects of ADP-ribosylation of desmin on filament polymerization and depolymerization were ...
Yuan, Jing
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Cytoskeletal derangements in hereditary myopathy with a desmin L345P mutation
, 2002 Patients with abnormal accumulations of desmin have been described in myopathies with or without cardiac involvement. Desmin deposits were sometimes associated with abnormal aggregates of other cytoskeletal proteins.
Carlsson, Lena, +5 more
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11‐year‐old girl presenting with blurred vision and progressive right arm weakness
Brain Pathology, EarlyView.
Trung Toan Tran +6 more
wiley +1 more source
Histopathology, EarlyView.Orcein is more sensitive than EVG for detecting intramural and extramural large vessel (venous) invasion than EVG and H&E in colorectal cancer. Background Large vessel invasion (VI) is a well‐established adverse prognostic factor in colorectal cancer (CRC).
Timothy Law +3 more
wiley +1 more source
Role of intermediate filament desmin in development of desmin-related myopathy [Elektronisk resurs]
, 2015 Desmin is a major intermediate filament of muscle cells, serving to transmit mechanical forces and propagate mechanochemical signals, to coordinate contraction and relaxation cycles, and to stabilize the positioning of cellular organelles, e.g ...
Smolina, N,
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