Results 91 to 100 of about 57,573 (289)
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf +7 more
wiley +1 more source
PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma. [PDF]
BackgroundLeiomyosarcoma (LMS) is a common type of soft tissue sarcoma that responds poorly to standard chemotherapy. Thus the goal of this study was to identify novel selective therapies that may be effective in leiomyosarcoma by screening cell lines ...
Al-Awar, Rima +11 more
core +2 more sources
Ossifying spindled and epithelioid tumour (OSET) can show unusual morphologic features, including minimal or absent peripheral ossification, eosinophil‐rich stroma, increased mitotic activity (≥5 mitotic figures per 10 high‐power fields), and necrosis.
Rayan M Sibira +9 more
wiley +1 more source
This study investigates the morphological and morphometric characteristics of the heart and great arteries in the common pheasant (Phasianus colchicus). Five adult male bird were used.
Hadis Ramezani, Nader Goodarzi
doaj +1 more source
The 68,000-Dalton Neurofilament-Associated Polypeptide is a Component of Nonneuronal Cells and of Skeletal Myofibrils [PDF]
Purified preparations of 10-nm neurofilaments from rat spinal cord and bovine or porcine brain contain a predominant 68,000-dalton polypeptide. This polypeptide is also a major component of the neurofilaments that copurify with brain tubulin isolated by ...
Asai, David J. +2 more
core
Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression [PDF]
Endothelial Wnt/β-catenin signaling is necessary for angiogenesis of the central nervous system and blood–brain barrier (BBB) differentiation, but its relevance for glioma vascularization is unknown. In this study, we show that doxycycline-dependent Wnt1
Abramsson +79 more
core +1 more source
P.149 Differential expression of intermediate filament proteins: lamins A/C and desmin within and between adult skeletal muscles [PDF]
Emad I. H. Shaqoura +3 more
openalex +1 more source
Development of the abdominal musculature in the chicken embryo
In this study, we investigate anatomy, morphogenesis, segmental origin, and fiber formation of the abdominal musculature in the chicken embryo. We show that abdominal muscles arise from somites 24 to 28, and that the segmental identity of individual fibers in the abdominal muscle sheets is maintained.
Margarethe Draga +6 more
wiley +1 more source
Progressive Structural Defects in Canine Centronuclear Myopathy Indicate a Role for HACD1 in Maintaining Skeletal Muscle Membrane Systems [PDF]
Mutations in HACD1/PTPLA cause recessive congenital myopathies in humans and dogs. Hydroxyacyl-coA dehydratases are required for elongation of very long chain fatty acids, and HACD1 has a role in early myogenesis, but the functions of this striated ...
Agrawal +92 more
core +3 more sources

