Results 71 to 80 of about 33,865 (165)

Senescent Myoblasts Exhibit ROS‐Dependent Akt‐mTORC1 Dysregulation and Are Susceptible to Reductive Stress‐Induced Cell Death

Aging Cell, Volume 25, Issue 6, June 2026.
Senescent myoblasts exhibit dysregulated Akt/mTORC1 signalling. Antioxidants can alleviate this dysregulation, as well as other downstream senescent phenotypes. Moreover, prolonged antioxidant treatment can selectively induce cell death in senescent myoblasts, suggesting that these cells are more susceptible to reductive stress.
Vladimir Belhac, Alex Dillingham, Emilia Coward, Bradley Teal, Mark C. Turner, Stephanie D. Gagnon, Jiani Qian, Harry Wilford, Ella Warren, Natalie Moger, Bernadette Carroll, Owen G. Davies, Hannah F. Dugdale, Neil R. W. Martin   +13 more
wiley   +1 more source

Pregnancy shifts endothelial progenitor cell morphology and function: Role of metabolism, pro‐inflammatory cytokines and fetal sex

The Journal of Physiology, Volume 604, Issue 11, Page 4585-4604, 1 June 2026.
Abstract figure legend We recruited non‐pregnant women (NP), women in early pregnancy (EP) and late pregnancy (LP) for isolation of endothelial colony forming cells (ECFCs) via density gradient centrifugation. Plasma supernatant was collected for analysis of markers of glucose and lipid metabolism (fasting glucose, triglycerides, cholesterol, low ...
Marie‐Therese Weiser‐Fuchs, Andreas Jantscher, Simone Tischler, Elena Osto, Lusik Balayan, Hubert Scharnagl, Gabriele Jäger, Bettina Amtmann, Azra Kulovic‐Sissawo, Sabrina Puster, Herbert Fluhr, Barbara Obermayer‐Pietsch, Christina Stern, Ursula Hiden, Evelyn Jantscher‐Krenn   +14 more
wiley   +1 more source

Desmin myopathy: Distinct filamentopathy caused by mutations in the desmin gene

, 2016
Intermediate filaments are 10 nm structures that interact with actin and microtubules to form the cytoskeletal scaffolding of the cells. They share a common structure of a dimer with 2 alpha helical chains intertwined in a coiled-coil highly conserved rod structure.
Dalakas, M, Vasconcelos, O, Kaminska, A, Kwiesciski, H, Hilton-Jones, D, Squier, W, Goldfarb, L   +6 more
openaire   +1 more source

Desmin Immunoreactivity in Glomus Tumors [PDF]

American Journal of Clinical Pathology, 1987
J J, Brooks, M, Miettinen, I, Virtanen
openaire   +2 more sources

3-Dimensional reconstruction reveals frequent intraluminal growth of submucosal veins in surgically resected pT1 colorectal cancers. [PDF]

J Pathol Transl Med
Park J, Kim MJ, Kim YW, Lee BW, Shin J, Shin J, Pack CG, Yang DH, Kim J, Park IJ, Hruban RH, Hong SM.   +11 more
europepmc   +1 more source

Oral malignant melanoma with rhabdoid cell differentiation and myogenic features in a dog. [PDF]

J Vet Med Sci
Yamaguchi M, Mineshige T, Kakinuma Y, Shiga T, Aihara N, Kayanuma H, Kamiie J.   +6 more
europepmc   +1 more source

Identification and Functional Analysis of Dual Nuclear Localization Signals on Desmin. [PDF]

ACS Omega
Kural Mangit E, Dinçer P.
europepmc   +1 more source

Role of intermediate filament desmin in development of desmin-related myopathy

, 2015
Desmin is a major intermediate filament of muscle cells, serving to transmit mechanical forces and propagate mechanochemical signals, to coordinate contraction and relaxation cycles, and to stabilize the positioning of cellular organelles, e.g. mitochondria. Around 70 desmin gene mutations have been reported in conjunction with desmin-related myopathy.
openaire   +1 more source

Immunoreactivity for CD34, Desmin, Keratins, KIT, Alpha-Smooth Muscle Actin, S100, and Vimentin in Malignant Mesenchymal Neoplasms in Guinea Pigs: A Series of 62 Cases From a Single Institution. [PDF]

Vet Med Sci
Lenz J, Škorič M, Tichý F, Fiala L.
europepmc   +1 more source

A hepatic solitary fibrous tumor with giant cells and a review of the literature. [PDF]

Discov Oncol
Zhao B, Zhou S, Qu J, Gao X, Wang X, Yang C, Tong Q, Zheng L.   +7 more
europepmc   +1 more source