Results 121 to 130 of about 72,501 (324)

A case report of a rare intramuscular granular cell tumor [PDF]

, 2015
Background: Granular cell tumors (GCTs) were firstly described by Weber in 1854 and 70 years later by Abrikossoff and classified as benign tumors. Originally considered muscle tumors, they have been identified as neural lesions, due to their close ...
Cacciotti, Jessica, Cirenza, Mirko, DELLA ROCCA, Carlo, Labate, Agata, Laghi, Andrea, Lo Schiavo, Maria Grazia, Mazzitelli, Riccardo, Petrozza, Vincenzo, Porta, Natale   +8 more
core   +1 more source

Gain-of-function mutation in ubiquitin-ligase KLHL24 causes desmin degradation and dilatation in hiPSC-derived engineered heart tissues.

Journal of Clinical Investigation, 2021
M. Vermeer, M. Bolling, J. Bliley, K. A. Arevalo Gomez, Mario G. Pavez-Giani, D. Kramer, Pedro H Romero-Herrera, B. Westenbrink, G. Diercks, M. P. van den Berg, A. Feinberg, Herman H. W. Silljé, P. van der Meer   +12 more
semanticscholar   +1 more source

Targeting SPP1‐CD44‐Hedgehog Axis Elicits Therapeutic Effects in Hepatocellular Carcinoma by Suppressing Intratumoral Fibrosis

Cancer Science, EarlyView.
SPP1 was identified as a key driver of intratumoral fibrosis and hepatocellular carcinoma (HCC) progression through transcriptomic, histological, and functional analyses. Mechanistically, SPP1 promotes HSC activation and fibrosis via the SPP1–CD44–GLI1 axis, and pharmacologic inhibition of Hedgehog signaling effectively reduces tumor growth and ...
Atsushi Nara, Shu Shimada, Yoshimitsu Akiyama, Megumi Hatano, Yusuke Chino, Suguru Miyazawa, Hanako Tamura, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Shuichi Watanabe, Eriko Katsuta, Keiichi Akahoshi, Kenichi Ohashi, Minoru Tanabe, Daisuke Ban, Shinji Tanaka   +16 more
wiley   +1 more source

P.149 Differential expression of intermediate filament proteins: lamins A/C and desmin within and between adult skeletal muscles [PDF]

, 2022
Emad I. H. Shaqoura, E. McCallion, H. Fuller, M. Bowerman   +3 more
openalex   +1 more source

Influenza A Virus (H1N1) Infection Induces Ferroptosis to Promote Developmental Injury in Fetal Tissues

Cell Proliferation, EarlyView.
H1N1 infection during pregnancy specifically targets the fetal liver and lungs, triggering immune responses, tissue fibrosis and ferroptosis in parenchymal cells, ultimately leading to adverse pregnancy outcomes, offering insights into managing maternal H1N1 infections and their impact on fetal health.
Yuxi Jiang, Yao Shen, Qiongyin Zhang, Zi Liu, Yuzhen Liu, Jiaojiao Peng, Xuesong Yang, Feng Gao, Xiang‐Hong Ou, Qing‐Yuan Sun, Qiao Zhang, Guang Wang   +11 more
wiley   +1 more source

FEATURES OF ENDOMETRIAL STROMA DECIDUALIZATION IN EARLY PREGNANCY LOSS

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Background. Decidualization of the endometrial stroma is a multistage process. The immunohistochemical marker of differentiation of decidual cells is desmin. Purpose of the study.
Luchko E. V., Shtabinskaya T. T., Zubritsky M. G., Basinskiy V. A.   +3 more
doaj   +1 more source

Cell-free Embryonic Stem Cell Extract-mediated Derivation of Multi-potent Stem Cells from NIH3T3 Fibroblasts for Functional and Anatomical Ischemic Tissue Repair [PDF]

, 2007
The oocyte-independent generation of multipotent stem cells is one of the goals in regenerative medicine. We report that upon exposure to mouse ES cell (ESC) extracts, reversibly permeabilized NIH3T3 cells undergo de-differentiation followed by stimulus ...
Deepali Ahluwalia, Douglas W. Losordo, Erin Lambers, Evelyn Bord, Gangjian Qin, Hiromichi Hamada, Ilona Goukassian, Johnson Rajasingh, Karen Schlauch, Kenneth M. Rosen, Prasanna Krishnamurthy, Raj Kishore, Tina Thorne, Yan Zhu   +13 more
core   +1 more source

Acral Mesenchymal Spindle Cell Neoplasm With a Novel HMGA2::NCOA2 Fusion

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Molecular profiling has revolutionized the field of soft tissue pathology, enhancing diagnostic precision and treatment strategies. The integration of molecular analysis and immunohistochemistry has been crucial for classifying diagnostically challenging acral mesenchymal neoplasms.
Grace Z. Armstrong, Carina A. Dehner, Eitan Halper‐Stromberg, Esther Baranov, Anna C. Eden, Rachel P. Kowal   +5 more
wiley   +1 more source

Editorial: Intermediate filaments structure, function, and clinical significance

Frontiers in Cell and Developmental Biology, 2022
Dolores Pérez-Sala, Ming Guo
doaj   +1 more source

Atypical Fibroxanthoma/Pleomorphic Dermal Sarcoma With Osseous Metaplasia: A Series of Three Cases

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) are rare mesenchymal tumors typically arising on sun‐damaged skin of the head and neck in elderly patients. PDS is a more aggressive tumor but with similar demographics, cellular morphology, immunohistochemical features, and genetic findings.
Taylor Novice, Yitong Xu, Thomas Brenn, Scott C. Bresler   +3 more
wiley   +1 more source