Results 11 to 20 of about 50,053 (275)

Optimization of gelatin nanofabrication as a potential biocompatible nanocarrier

Archives of Pharmaceutical Sciences Ain Shams University, 2023
Gelatin is a promising natural biomaterial used as a drug delivery system for various indications. It is a cheap, abundant and safe protein derived from collagen with proved biodegradation, biocompatibility and non-immunogenicity. According to its source,
Nada A. Hussein, Ghada M. El Zaafarany , Mona M. A. Abdelmottaleb, Gehanne A. S. Awad   +3 more
doaj   +1 more source

Controlling desolvation through polymer-assisted grinding [PDF]

CrystEngComm, 2022
The ability to controllably desolvate a crystal-solvate system in a step-wise fashion through polymer-assisted grinding is demonstrated by varying the type and proportion of polymer agent used.
Maxwell W. Terban, Leillah Madhau, Aurora J. Cruz-Cabeza, Peter O. Okeyo, Martin Etter, Armin Schulz, Jukka Rantanen, Robert E. Dinnebier, Simon J. L. Billinge, Mariarosa Moneghini, Dritan Hasa   +10 more
openaire   +7 more sources

COMF: Comprehensive Model-Fitting Method for Simulating Isothermal and Single-Step Solid-State Reactions

Crystals, 2020
It is well known that the implementation of the conventional model-fitting (CMF) method leads to several indistinguishable ‘best’ candidate models (BCMs) for a single-step isothermal solid-state reaction (ISSR), meaning that subjective ...
Yannis Vasilopoulos, Eliška Skořepová, Miroslav Šoóš   +2 more
doaj   +1 more source

Solvent and solvation effects on reactivities and mechanisms of phospho group transfers from phosphate and phosphinate esters to nucleophiles

Frontiers in Chemistry, 2023
Organophosphorus esters fulfil many industrial, agricultural, and household roles. Nature has deployed phosphates and their related anhydrides as energy carriers and reservoirs, as constituents of genetic materials in the form of DNA and RNA, and as ...
Ikenna Onyido, Onyeka F. Obumselu, Chinyelu I. Egwuatu, Nkechi H. Okoye   +3 more
doaj   +1 more source

Wet Chemical Synthesis of Non-solvated Rod-Like α'-AlH3 as a Hydrogen Storage Material

Frontiers in Chemistry, 2020
Aluminum hydride (AlH3) is a promising candidate for hydrogen storage due to its high hydrogen density of 10 wt%. Several polymorphs of AlH3 (e.g., α, β, and γ) have been successfully synthesized by wet chemical reaction of LiAlH4 and AlCl3 in ether ...
Haizhen Liu, Hongyu Ma, Longfei Zhang, Shichao Gao, Xinhua Wang, Li Xu, Shuangyu Liu, Xiantun Huang, Chenglin Lu, Hui Luo, Hua Ning, Zhiqiang Lan, Jin Guo   +12 more
doaj   +1 more source

Toward an Understanding of the Formation and Desolvation of Methanol Solvate, and Structure of Methanolysis Product: A Case Study of Nicosulfuron

Crystals, 2020
Nicosulfuron (NS) is a widely used sulfonylurea herbicide because of its high selectivity, broad spectrum of herbicide activity, and excellent performance.
Huaxiang Zhu, Bei Zhang, Di Wu, Xiaowei Cheng, Guiping Li, Jun Xu, Lina Zhou, Wei Chen   +7 more
doaj   +1 more source

Maleate salts of bedaquiline

Acta Crystallographica Section E: Crystallographic Communications, 2021
Bedaquiline is one of two important new drugs for the treatment of drug-resistant tuberculosis (TB). It is marketed in the US as its fumarate salt, but only a few salts of bedaquiline have been structurally described so far.
Matthias Zeller, Susan Bogdanowich-Knipp, Pamela Smith, Dale K. Purcell, Mercy Okezue, Daniel T. Smith, Stephen R. Byrn, Kari L. Clase   +7 more
doaj   +1 more source

Development of Carvedilol-Loaded Albumin-Based Nanoparticles with Factorial Design to Optimize In Vitro and In Vivo Performance

Pharmaceutics, 2023
Carvedilol, an anti-hypertensive medication commonly prescribed by healthcare providers, falls under the BCS class II category due to its low-solubility and high-permeability characteristics, resulting in limited dissolution and low absorption when taken
Mohamed S. Attia, Mohamed F. Radwan, Tarek S. Ibrahim, Tarek M. Ibrahim   +3 more
doaj   +1 more source

Desolvation Processes in Channel Solvates of Niclosamide

Molecular Pharmaceutics, 2023
The antiparasitic drug niclosamide (NCL) is notable for its ability to crystallize in multiple 1:1 channel solvate forms, none of which are isostructural. Here, using a combination of time-resolved synchrotron powder X-ray diffraction and thermogravimetry, the process-induced desolvation mechanisms of methanol and acetonitrile solvates are investigated.
Jen E. Mann, Renee Gao, Shae S. London, Jennifer A. Swift   +3 more
openaire   +2 more sources

Building solids inside nano-space: from confined amorphous through confined solvate to confined ‘metastable’ polymorph [PDF]

, 2015
The nanocrystallisation of complex molecules inside mesoporous hosts and control over the resulting structure is a significant challenge. To date the largest organic molecule crystallised inside the nano-pores is a known pharmaceutical intermediate – ROY
Aceves-Hernandez, Alcoutlabi, Allen, Andronis, Andronis, Andronis, Andronis, Argyo, Babonneau, Beck, Beiner, Borka, Bradley, Carpentier, Charnay, Chen, Crowley, D. E. Braun, Dalal, David, Elmer, Etter, Guilbaud, Ha, Ha, Ha, Haller, Haller, Hamdi, Hamilton, Hamilton, Hamilton, Han, J. Tedder, Jackson, Jackson, Joshi, K. P. Nartowski, Karmwar, Kistenmacher, Kiwilsza, Kolodziejski, L. Fábián, Legendre, Limnell, Lohani, Lu, Lukens, Manzano, Manzano, Markvardsen, Masuda, Nassivera, Otsuka, Otsuka, Rengarajan, Sharma, Son, Stowell, Surwase, Ukmar, Ukmar, Ukmar, Vallet-Regi, Van Speybroeck, Wang, Y. Z. Khimyak, Yoshioka, Zhang, Zhao   +69 more
core   +1 more source