Results 11 to 20 of about 34,779 (287)

Kinetics of Desolvation-Mediated Protein–Protein Binding [PDF]

Biophysical Journal, 2000
The role of desolvation in protein binding kinetics is investigated using Brownian dynamics simulations in complexes in which the electrostatic interactions are relatively weak. We find that partial desolvation, modeled by a short-range atomic contact potential, is not only a major contributor to the binding free energy but also substantially increases
Camacho, Carlos J., Kimura, S.R., DeLisi, Charles, Vajda, Sandor   +3 more
openaire   +3 more sources

Modified Desolvation Method Enables Simple One-Step Synthesis of Gelatin Nanoparticles from Different Gelatin Types with Any Bloom Values [PDF]

Pharmaceutics, 2021
Gelatin nanoparticles found numerous applications in drug delivery, bioimaging, immunotherapy, and vaccine development as well as in biotechnology and food science.
Pavel Khramtsov, Oksana Burdina, Sergey Lazarev, Anastasia Novokshonova, Maria Bochkova, Valeria Timganova, Dmitriy Kiselkov, Artem Minin, Svetlana Zamorina, Mikhail Rayev   +9 more
doaj   +2 more sources

Desolvation Processes in Channel Solvates of Niclosamide

Molecular Pharmaceutics, 2023
The antiparasitic drug niclosamide (NCL) is notable for its ability to crystallize in multiple 1:1 channel solvate forms, none of which are isostructural. Here, using a combination of time-resolved synchrotron powder X-ray diffraction and thermogravimetry, the process-induced desolvation mechanisms of methanol and acetonitrile solvates are investigated.
Jen E. Mann, Renee Gao, Shae S. London, Jennifer A. Swift   +3 more
openaire   +3 more sources

The role of surface charge in the desolvation process of gelatin: implications in nanoparticle synthesis and modulation of drug release

International Journal of Nanomedicine, 2017
Saad M Ahsan, Chintalagiri Mohan Rao Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Hyderabad, Telangana, India Abstract: The process of moving hydrophobic amino acids into the core of a protein by desolvation
Ahsan SM, Rao CM
doaj   +1 more source

Ion desolvation for boosting the charge storage performance in Ti3C2 MXene electrode

Nature Communications
Clarifying the relationship between ion desolvation, ion-electrode interactions, and charge storage capacity during ion intercalation in host electrode materials is crucial for advancing fast and efficient energy storage systems.
Zheng Bo, Rui Wang, Bin Wang, Sanjay Sunny, Yuping Zhao, Kangkang Ge, Kui Xu, Yajing Song, Encarnacion Raymundo-Piñero, Zifeng Lin, Hui Shao, Qian Yu, Jianhua Yan, Kefa Cen, Pierre-Louis Taberna, Patrice Simon   +15 more
doaj   +2 more sources

Direct evidence of acid-driven protein desolvation

Proceedings of the National Academy of Sciences
Water and its ability to modulate the protonation states of biomolecules govern the physical chemistry of life, dictating their metabolic functions. However, how amino acid protonation alters protein hydration and solubility is an open question since Kuntz and Kauzmann proposed p H -driven ...
Farzad Hamdi, Ioannis Skalidis, Inken Kaja Schwerin, Jaydeep Belapure, Dmitry A. Semchonok, Fotis L. Kyrilis, Christian Tüting, Johannes Müller, Georg Künze, Panagiotis L. Kastritis   +9 more
core   +4 more sources

Toward Controlled Partial Desolvation of Guest Responsive Metal Organic Frameworks for Precise Porosity Control

, 2023
Desolvation of guest responsive metal organic frameworks MOFs under dynamic vacuum often leads to the collapse of the pores, whereas supercritical CO2 SC CO2 drying is found to be the best alternative way to overcome the challenge of MOF desolvation.
Kaskel, S., Maity, K., Bon, V.
core   +3 more sources

Disclosing the interfacial electrolyte structure at Na-insertion electrode materials: origins of desolvation phenomenon [PDF]

, 2023
Among a variety of promising cathode materials for Na-ion batteries, polyanionic Na-insertion compounds are among the preferred choice due to known fast sodium transfer through the ion channels along their framework structures.
Kateryna, Goloviznina, Ezzoubair, Bendadesse, Mathieu, Salanne, Jean-Marie, Tarascon, Ozlem, Sel   +4 more
core   +3 more sources

Towards controlled partial desolvation of guest-responsive Metal-Organic Frameworks for precise porosity control [PDF]

, 2023
Desolvation of guest responsive metal-organic frameworks (MOFs) under dynamic vacuum often leads to the collapse of the pores whereas supercritical CO2 (SC-CO2) drying was found to be the best alternative way to overcome the challenge of MOF desolvation.
Volodymyr, Bon, Stefan, Kaskel, Kartik, Maity, Stefan Kaskel, Kartik Maity, Volodymyr Bon   +5 more
core   +2 more sources

Cascade Desolvation and Conversion Reaction Driven by Self-Tandem Catalysis for Wide-Temperature Li-S Batteries. [PDF]

Adv Sci (Weinh)
A self‐tandem catalysis accelerating cascade reaction strategy is pioneered through constructing electron‐adjustable atom‐level Ce as the self‐tandem catalyst to lower energy barriers for fast Li+ desolvation and sequential sulfur conversion kinetics. The catalyzed cells operate effectively over a wide‐temperature range from 0 to ‐30 °C, delivering a ...
Zhang J, Yin S, Yang M, Li H, You C, Tian N, Cao Z, Zhang Y, Duan R, Lin H, Wang J.   +10 more
europepmc   +2 more sources