Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry
Data in Brief, 2016 A reference monoclonal antibody IgG1 and a fusion IgG protein were analyzed by top- and middle-down mass spectrometry with multiple fragmentation techniques including electron transfer dissociation (ETD) and matrix-assisted laser desorption ionization in-
Bao Quoc Tran +10 more
doaj +1 more source
Safety Science and Technology, EarlyView.Thermal degradation mechanism and kinetic triplets of Nafion N115 were elucidated via TGA, kinetic compensation analysis, Sestak–Berggren reconstruction, quantum calculations, and GC–MS. A diffusion‐controlled model governs active pyrolysis, although persistent perfluorinated products were identified, highlighting environmental implications and ...
Fan Yang +6 more
wiley +1 more source
Intraoperative Mass Spectrometry in Oncology: Technologies, Clinical Applications, and Challenges
MoleculesSurgical precision is critical in oncology, where complete tumor resection while preserving healthy tissue directly influences patient outcomes. Traditional intraoperative diagnostic tools, such as frozen-section analysis, are limited by time constraints,
Robert Onulov +4 more
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Natural Product Communications, 2012 The physical properties and molecular structure of five natural indole alkaloids (IAs) and their interaction with protein targets have been studied, experimentally and theoretically.
Bojidarka Ivanova, Michael Spiteller
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Nonthermal plasma approaches for combating implant‐associated infections: A compendious review
VIEW, EarlyView.Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe +8 more
wiley +1 more source
Dehydration‐driven organization of metabolites into NaDES‐like assemblies in orthodox seeds
New Phytologist, EarlyView.Summary Desiccation tolerance in plants, especially during orthodox seed dehydration, relies on compatible solute accumulation, complex molecular mechanisms, and intermolecular organizations that remain poorly understood. We combined metabolite profiling, mass spectrometry imaging, and electrospray and cold‐spray ionization mass spectrometry to ...
Youcef Haddad +11 more
wiley +1 more source
Tandem mass spectrometry imaging to assess illudin S distributions in Omphalotus illudens mushrooms
Talanta OpenPoisoning metabolites within mushrooms typically exert varying physiological and biological effects; however, their distributions within mushrooms are seldom investigated.
Shigeki Matsui +2 more
doaj +1 more source
Cyclodextrins tethered with oligolactides – green synthesis and structural assessment
Beilstein Journal of Organic Chemistry, 2017 Biodegradable oligolactide derivatives based on α-, β- and γ-cyclodextrins (CDs) were synthesized by a green procedure in which CDs play the role of both the initiator and the catalyst.
Cristian Peptu +4 more
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Study of the mainstream cigarette smoke aerosols by Fourier transform ion cyclotron resonance mass spectrometry coupled to laser/desorption and electrospray ionization – Additional insights on the heteroaromatic components [PDF]
, 2018 Adama Kamissoko +3 more
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Photochemistry and Photobiology, EarlyView.Scaffold hopping strategy used to develop chalcones structure‐related to the avobenzone tautomer. Positive aspects of 2‐hydroxychalcones are highlighted. Abstract Chalcones are α,β‐unsaturated ketones with extended π‐conjugation, making them promising scaffolds for the development of organic UV filters.
Gabriela Zanella Marcon +11 more
wiley +1 more source