Results 111 to 120 of about 376,084 (233)

Advancing proteomics with ion/ion chemistry Mass Spectrometry For Proteomics Analysis

BioTechniques, 2006
Mass spectrometers, instruments that use electric and/or magnetic fields to measure a gas-phase ion's mass-to-charge ratio (m/z), are used in a wide variety of applications—with the field having a reputation for providing good sensitivity and high ...
David M. Good, Joshua J. Coon
doaj   +1 more source

Surface Engineering of Ti3C2Tx MXenes via Silanol Functionalization for Improved Electrochemical Performance

Small, EarlyView.
This study explores the covalent functionalization of Ti3C2Tx using 5,5′‐bis(triisopropoxysilyl)‐2,2′‐bipyridine in different solvents, revealing that only m‐xylene enables effective covalent bonding, ensuring structural stability and preventing layer swelling.
Abelardo Sánchez‐Oliva, Verónica Montes‐García, Ke Li, Kaitlyn Prenger, Xuyun Guo, Iwona Janica, Wojciech Kukułka, Adrián Tamayo, Pilar Prieto, Paolo Samorì, Valeria Nicolosi, Artur Ciesielski   +11 more
wiley   +1 more source

Physical Properties and Molecular Conformations of Indole Alkaloids and Model Protein Interactions – Theoretical Experimental Study

Natural Product Communications, 2012
The physical properties and molecular structure of five natural indole alkaloids (IAs) and their interaction with protein targets have been studied, experimentally and theoretically.
Bojidarka Ivanova, Michael Spiteller
doaj   +1 more source

Hydroxycinnamic Acid Amides Emerge as Multifunctional Molecules Involved in Regeneration and Volatile Signalling During Wound Responses

Plant, Cell &Environment, EarlyView.
ABSTRACT Hydroxycinnamic acid amides (HCAAs) are phenylpropanoid‐derived metabolites traditionally associated with antimicrobial defence and cell wall reinforcement during plant–pathogen interactions. However, their contribution to plant responses to mechanical injury, particularly in wound healing and damage‐induced signalling, remains poorly ...
Carmen Grech‐Hernández, Andrade Cynthia, Francisco Vera‐Sirera, Álvaro Luis Jiménez‐Jiménez, Marc Valls, Nuria S. Coll, Ismael Rodrigo, José María Bellés, María Pilar López‐Gresa, Purificación Lisón   +9 more
wiley   +1 more source

Development of chalcones structure‐related to avobenzone: Photoprotection, photostability, and safety evaluation

Photochemistry and Photobiology, EarlyView.
Scaffold hopping strategy used to develop chalcones structure‐related to the avobenzone tautomer. Positive aspects of 2‐hydroxychalcones are highlighted. Abstract Chalcones are α,β‐unsaturated ketones with extended π‐conjugation, making them promising scaffolds for the development of organic UV filters.
Gabriela Zanella Marcon, Taíne de Bastos Brum, Nayara Fernanda Tokashike de Araujo, Gabriela Lascala Ramos, Bruna Cogo Borin, Ruth Barin, Aline Ferreira Ourique, André Passaglia Schuch, Andréa Inês Horn Adams, Lorena Rigo Gaspar Cordeiro, Letícia Cruz, Fernando Fumagalli   +11 more
wiley   +1 more source

Spatially Resolved Plant Metabolomics

Metabolites
Research and innovation in metabolomics tools to measure metabolite accumulation within plants have led to important discoveries with respect to the improvement of plant stress tolerance, development, and crop yield.
Ronald J. Myers, Zachary M. Tretter, Abigail G. Daffron, Eric X. Fritschi, William Thives Santos, Maiya L. Foster, Matthew Klotz, Kristin M. Stafford, Christina Kasch, Thomas J. Taylor, Lillian C. Tellefson, Tyler Hartman, Dru Hackler, Preston Stephen, Lloyd W. Sumner   +14 more
doaj   +1 more source

Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry

Data in Brief, 2016
A reference monoclonal antibody IgG1 and a fusion IgG protein were analyzed by top- and middle-down mass spectrometry with multiple fragmentation techniques including electron transfer dissociation (ETD) and matrix-assisted laser desorption ionization in-
Bao Quoc Tran, Christopher Barton, Jinhua Feng, Aimee Sandjong, Sung Hwan Yoon, Shivangi Awasthi, Tao Liang, Mohd M. Khan, David P.A. Kilgour, David R. Goodlett, Young Ah Goo   +10 more
doaj   +1 more source

Spatially Resolved Metabolomics of Optimal Cutting Temperature (OCT) Compound‐Embedded Tumors

International Journal of Cancer, Volume 159, Issue 12, Page 3038-3048, 15 December 2026.
ABSTRACT Mass spectrometry imaging (MSI) is emerging as a powerful tool for uncovering the distribution of metabolites in the tumor microenvironment and studying tumor metabolism in vivo. To date, MSI of biobanked tissues contextualized by patient data has been limited to peptides, proteins, and glycans—with few examples for metabolites.
Joseph Monaghan, Nicholas Woytowich, Tian Zhao, Kiera Nguyen, Emily Mahony, Julian J. Lum, Kyle D. Duncan   +6 more
wiley   +1 more source

Manipulation of Protein Charge States through Continuous Flow-Extractive Desorption Electrospray Ionization: A New Ambient Ionization Technique

, 2016
Manipulation of protein charge states in electrospray ionization-mass spectrometry (ESI-MS) has implications for the study of intact proteins, protein−protein interactions, post-translational modifications, and protein sequencing.
Brian L. Edwards (1943161), Kevin A. Schug (1402753), Samuel H. Yang (2234740), Li Li (14993), Aruna B. Wijeratne (1672738)   +4 more
core   +1 more source

Intraoperative Mass Spectrometry in Oncology: Technologies, Clinical Applications, and Challenges

Molecules
Surgical precision is critical in oncology, where complete tumor resection while preserving healthy tissue directly influences patient outcomes. Traditional intraoperative diagnostic tools, such as frozen-section analysis, are limited by time constraints,
Robert Onulov, Marius Georgescu, Corina Flangea, Adela Chirita-Emandi, Alina-Florina Serb   +4 more
doaj   +1 more source