Results 91 to 100 of about 176,325 (235)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Exploring the Personality Traits of Portugal as a Tourist Destination: Perspective of the Czech Market [PDF]

Journal of Spatial and Organizational Dynamics, 2015
The personality of a destination is vital to build a coherent destination brand and strengthen the place identity. Furthermore, brand personality appears in literature as a strategic axis that can be explored by tourist destinations in order to ...
Manuela Guerreiro, Dora Agapito, Matěj Pech   +2 more
doaj  

ANALISIS POTENSI DESTINATION BRAND EXPERIENCE KOTA TEGAL PADA INTENSI REKOMENDASI DAN INTENSI KUNJUNGAN KEMBALI DENGAN KEPUASAN SEBAGAI VARIABEL MEDIASI

Monex: Journal Research Accounting Politeknik Tegal, 2019
Sedikitnya penelitian mengenai pengukuran merek destinasi mengindikasikan bagaimana sulitnya mengevaluasi sebuah merek destinasi. Peneliti membahas destination branding dengan sebuah konsep baru, destination brand experience (DBE), yang menyajikan ...
Ghea Dwi Rahmadiane, Nurul Mahmudah, Yusri Anis Faidah   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Is Gastronomy A Relevant Factor for Sustainable Tourism? An Empirical Analysis of Spain Country Brand [PDF]

, 2019
Tourism has become a fundamental industry for the economic growth of many countries. Due to this, there is growing competitiveness among the different destinations to attract as many tourists as possible.
Leal Rodríguez, Antonio Luis, Sanchís Pedregosa, Carlos, Vázquez-Martínez, Ulpiano J.   +2 more
core   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The Effect of Visiting the Mystical Destination Brand on Love and Fascination with the Destination Brand (Case Study of Atar Neishaburi Tomb) [PDF]

International Journal of Tourism, Culture and Spirituality
Mystical tourism could have a significant role in the development of tourism industry. It is also possible to achieve a significant contribution by investing in the pristine sector of mystical tourism and create an authentic Iranian mystical cultural ...
Yazdan Shirmohammadi , Amin Ghanbari , Parastoo Amidi   +2 more
doaj   +1 more source

The Social Role of Design on Collaborative Destination Branding: Creating a new journey, a new story for the Waterfall Way, New South Wales, Australia [PDF]

, 2009
This paper suggests that collaborative design can be an effective tool to promote social change. A co-design methodology and the results of its application in branding the Waterfall Way (New South Wales, Australia) as an eco- and nature-based tourism ...
Haworth, Robert J, Spence, Rebecca, Taboada, Manuela   +2 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Destination brand licensing – the case of Porta Lubavia brand

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013
Destination branding is one of the most popular topic among tourism destinations researchers and practitioners however recent research revealed that it is a concept not clear.
Michał Żemła
doaj   +1 more source