Results 101 to 110 of about 176,325 (235)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
THE EVALUATION OF TOURISM DESTINATION BRAND EQUITY FROM THE FEMALE TOURIST'S PERSPECTIVES (STUDY OF 16 CITIES IN IRAN) [PDF]
Geo Journal of Tourism and Geosites, 2018 Despite the surge in interest in research on tourism destinations, little attention has been paid to investigating and comparing destination brand equity that implies conceptualizing how tourists evaluate a destination brand is complex.
Mohammad KAZEMI +3 more
doaj
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Enhancing Brand Image through Events and Cultural Festivals: the Perspective of the Stresa Festival’s Visitors [PDF]
, 2017 Cultural events have become a significant component within the strategies of destination branding of a place. Territories are increasingly using events and cultural festivals to enhance their image and boost tourism development.
Cerutti, S, Piva, L, Prats, L, Raj, R
core +5 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Navigating digital horizons: A systematic review of social media’s role in destination branding
Journal of Enterprise and DevelopmentPurpose — This study aims to acquire a comprehensive understanding of how social media platforms contribute to the process of destination branding by identifying major themes in the literature pertaining to social media's role in destination branding ...
Deske Wenske Mandagi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
The Influence of Previous Visitation on Customer's Evaluation of a Tourism Destination [PDF]
The paper investigates the customer's perspective on a tourism destination brand through four proposed dimensions: awareness, image, quality and loyalty dimension.
Maja Konecnik, Mitja Ruzzier
core
Conceptualizing residents' destination brand ambassador behavior [PDF]
, 2017 Although destination branding has become increasingly popular throughout the last decades, the role of the biggest destination brand stakeholder has scarcely been researched: the local inhabitants of a destination, commonly called the “resident ...
Hung, K., Wassler, Philipp
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source