Results 121 to 130 of about 176,325 (235)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Apprehending The Tour Operators Destination Brand Knowledge [PDF]
African Journal of Hospitality, Tourism and Leisure, 2019 The present study aims to understand and assess the tour operators destination brand knowledge of an Indian heritage tourism circuit the ‘Golden Triangle’. The concept has been measured utilizing Keller’s conceptual framework of the brand knowledge.
Dr. Kirti Singh Dahiya +1 more
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Critical Success Factors of Consumer-Based Brand Equity in Yazd Tourism Destination [PDF]
Muṭāli̒āt-i Mudīriyyat-i Gardishgarī, 2010 Tourism destination brand equity is defined as the brand assets (or liabilities) linked to a destination`s name and symbol that add to (or subtract from) the services and experiences provided.
mohammad hoseyn imani khoshkhou +1 more
doaj
Experiences and Tourism in Coastal Areas: Marketing the tourist experience at the English Riviera [PDF]
, 2015 This chapter examines the relationships between the branding and marketing of coastal destinations in England with the experiences and behaviour of tourists visiting those destinations.
Chapman, Anya, Rosslee, C.
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Rancangan Destination Brandingkabupaten Sinjai, Sulawesi Selatan [PDF]
, 2019 Kabupaten Sinjai belum memiliki branding khusus pariwisata sehingga dibutuhkan rancangan destination branding yang dapat menjadi alat promosi destinasi.
ERICK, J. A. (JILL) +4 more
core
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source