Results 41 to 50 of about 42,701 (261)
Formation of the Inbound Tourism Business Ecosystem:
Maketingu Janaru, 2020 Who and what comprise the tourism business ecosystem for the Japanese tourism market in Hawaii? To answer this question, this paper focused on the behavior of an international tour operator (JTB Hawaii) and conducted a case study from the viewpoint of ...
Chiharu Kashiwagi
doaj +1 more source
THE POTENTIALS AND POSSIBILITIES FOR DEVELOPMENT OF TOURISTIC OFFER IN EASTERN MACEDONIA [PDF]
Journal of Process Management and New Technologies, 2016 The research of the touristic offer market indicates that the previous touristic arrangements that included a touristic offer of seven or fourteen days is not an attractive offer nowadays.
Nikola Bizoev
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Aptisi Transactions on Technopreneurship, 2023 This research focuses on the high urgency of utilizing Artificial Intelligence (AI) and the Internet of Things (IoT) to enhance Smart Tourism Destinations (STDs).
Aliyah +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
SUSTAINABLE (RE)DEVELOPMENT OF TOURISM DESTINATIONS AS A PLEDGE FOR THE FUTURE – A CASE STUDY FROM THE WESTERN BALKANS [PDF]
Geo Journal of Tourism and GeositesThe study aims to analyse and thus obtain a comprehensive understanding of the current situation, issues, needs, and challenges related to the tourism sector in the five Western Balkans economies in the post-COVID-19 context.
Miroslav KNEŽEVIĆ +5 more
doaj +1 more source