Results 61 to 70 of about 616,829 (302)

A whole-of-life approach to tourism: The case for accessible tourism experiences [PDF]

open access: yes, 2009
This article examines the concept of a whole-of-life approach to tourism through presenting the case for 'accessible tourism'. The importance of this approach is that it has been estimated that 30% of a population will have access requirements at any ...
Darcy, S, Dickson, TJ
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Destination Unknown. Is There any Economics Beyond Tourism Areas? [PDF]

open access: yes
In recent years, several papers have been focussing on various aspects of the tourism destination. The destination is a central issue within tourism studies, embodying in one single concept all the specific and problematic features of tourism, such as ...
Guido Candela, Paolo Figini
core   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

SUSTAINABLE (RE)DEVELOPMENT OF TOURISM DESTINATIONS AS A PLEDGE FOR THE FUTURE – A CASE STUDY FROM THE WESTERN BALKANS [PDF]

open access: yesGeo Journal of Tourism and Geosites
The study aims to analyse and thus obtain a comprehensive understanding of the current situation, issues, needs, and challenges related to the tourism sector in the five Western Balkans economies in the post-COVID-19 context.
Miroslav KNEŽEVIĆ   +5 more
doaj   +1 more source

An Uncertain Destination: On the Development of Conflict Management Systems in U.S. Corporations [PDF]

open access: yes, 2004
[Excerpt] Our survey and field research have led us to some tentative conclusions that do not conform to the conventional wisdom of our field. From its inception, ADR has been controversial.
Hall, Lavinia   +2 more
core   +1 more source

Determinants of tourism destination competitiveness in the countries most visited by international tourists: Proposal of a synthetic index [PDF]

open access: yes, 2019
Tourism destination competitiveness is a multidimensional concept that is widely studied in the academic literature, but multiple factors make its measurement a difficult task.
Azevedo, Paula Serdeira   +3 more
core   +2 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Applying the concept of foresight method for building tourism destination management scenarios

open access: yesBulletin of Geography. Socio-Economic Series
The article presents a methodological concept for the creation of tourism management foresight scenarios for selected areas of intervention and driving forces as well as the obligatory components influencing the directions of its evolution ...
Bartłomiej Walas   +4 more
doaj   +1 more source

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