Results 71 to 80 of about 42,701 (261)

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

The Superior Destination Experience

open access: yesJournal of Tourismology, 2017
Offering a desirable tourist experience is significant for destinations’ success. Although tourist experiences have been analysed in different settings, there is still scant research on which experiential characteristics make a superior destination. This
Gürel Çetin   +2 more
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Managing Asian Destinations

open access: yes, 2018
This book focuses on the planning, marketing, and management of Asian tourism destinations, and evaluates current developments within Southeast-Asia and the wider Asia-Pacific region.
Wang, Ying   +3 more
openaire   +2 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

UNCERTAIN POSITION AND SIGNIFICANCE OF DESTINATION MANAGEMENT ORGANISATIONS IN THE ENTIRE NETWORK OF DESTINATION STAKEHOLDERS – THE CASE OF CROATIA

open access: yesActa Economica et Turistica, 2021
Within numerous definition determinants, a tourism destination still predominantly represents a complex and dynamic system of numerous stakeholders related at a formal and non-formal level.
Damir Pavlović
doaj  

VARIATION OF DESTINATION IMAGE AND ITS INFLUENTIAL FACTORS: A CONCEPTUAL ANALYSIS [PDF]

open access: yesGeo Journal of Tourism and Geosites
Destination image is a fundamental concept in destination marketing that has attracted many research endeavors. Despite the plethora of studies on destination image, destination image as a concept is yet to be affirmed whether it is static or dynamic ...
Berislav ANDRLIĆ   +2 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Destination marketing management adjustment in situation of globalization and clusterization in tourism [PDF]

open access: yesMarketing (Beograd. 1991), 2009
Article describes few concepts: PPP (Public-Private Partnership), DMO (Destination Management Organization) and Clusters, that have recently came into focus in tourism policy worldwide.
Bakić Ognjen
doaj  

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