Results 101 to 110 of about 9,578,892 (276)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Design of Cross-Domain Relay Buoy Communication System Based on Multi-Source Communication Links
水下无人系统学报Aiming at the problems of limited communication modes, low reliability, weak scalability, and high power consumption existing in deep-sea submersible communication methods, this paper proposed a cross-domain relay buoy communication system design method ...
Guangsheng LI +3 more
doaj +1 more source
Object Detection in 20 Years: A Survey
, 2019 Object detection, as of one the most fundamental and challenging problems in computer vision, has received great attention in recent years. Its development in the past two decades can be regarded as an epitome of computer vision history.
Guo, Yuhong +3 more
core
A Deep Learning Approach to Drone Monitoring
, 2017 A drone monitoring system that integrates deep-learning-based detection and tracking modules is proposed in this work. The biggest challenge in adopting deep learning methods for drone detection is the limited amount of training drone images.
Aggarwal, Pranav +3 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
BMC Health Services ResearchBackground Barriers to the cancer continuum organization and interventions to approach them have been identified; however, there is a lack of a tool matching them.
Isabel Mosquera +4 more
doaj +1 more source
Continuous Wavelet Transform and Hidden Markov Model Based Target Detection [PDF]
, 2014 Standard tracking filters perform target detection process by comparing the sensor output signal with a predefined threshold. However, selecting the detection threshold is of great importance and a wrongly selected threshold causes two major problems ...
Efe, M., Tuğaç, S.
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Delaunay triangulation based image enhancement for echocardiography images [PDF]
, 2009 A novel image enhancement approach for automatic echocardiography image processing is proposed. The main steps include undecimated wavelet based speckle noise reduction, edge detection, followed by a regional enhancement process that employs Delaunay ...
Ahanathapillai, V. +2 more
core