Results 121 to 130 of about 9,578,892 (276)

Data-driven analysis of the beauty hadron production in pp collisions at the LHC with Bayesian unfolding

Journal of High Energy Physics
Heavy flavour production in proton-proton (pp) collisions provides insights into the fundamental properties of Quantum Chromodynamics (QCD). Beauty hadron production measurements are widely performed through indirect approaches based on their inclusive ...
Xiaozhi Bai, Guangsheng Li, Yifei Zhang, Qingyi Situ, Xiaolong Chen   +4 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Hepatic steatosis in postmenopausal women is characterized by distinct serum extracellular vesicle proteomic signatures

BMC Medicine
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is common among midlife women. Circulating extracellular vesicles (EVs) carry bioactive cargo that may mediate or reflect disease processes, but their role in hepatic steatosis ...
Patrick Pirrotte, Brooke Lovell, Siobán D. Harlow, Carrie A. Karvonen-Gutierrez, Michelle M. Hood, Ignazio S. Piras, Xiumei Wu, Melissa N. Martinez, Ritin Sharma, Krystine Garcia-Mansfield, Maya Willey, Johanna K. DiStefano   +11 more
doaj   +1 more source

Boosting Image Forgery Detection using Resampling Features and Copy-move analysis

, 2018
Realistic image forgeries involve a combination of splicing, resampling, cloning, region removal and other methods. While resampling detection algorithms are effective in detecting splicing and resampling, copy-move detection algorithms excel in ...
Bappy, Jawadul H., Bunk, Jason, Chandrasekaran, Shivkumar, Flenner, Arjuna, Manjunath, B. S., Mohammed, Tajuddin Manhar, Nataraj, Lakshmanan, Peterson, Lawrence, Roy-Chowdhury, Amit K.   +8 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Design of Low-SAR High-Efficiency Terminal Antenna Using Magnetic Field Homogenization

Micromachines
A low-SAR high-efficiency terminal antenna based on the magnetic field homogenization is proposed in this paper. Starting from the spatial correlation between the antenna’s near-field tangential magnetic field hotspots and SAR distribution, the influence
Sihan Xiao, Yong-Chang Jiao, Ziming Lv, Liupeng Zan, Zibin Weng   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Detecting retinoblastoma.

Community eye health, 2018
It is important to learn the early signs of retinoblastoma. Early detection, diagnosis and treatment depends on it.
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source