Results 81 to 90 of about 9,578,892 (276)

Artificial intelligence as an initial reader for double reading in breast cancer screening: a prospective initial study of 32,822 mammograms of the Egyptian population

The Egyptian Journal of Radiology and Nuclear Medicine
Background Although artificial intelligence (AI) has potential in the field of screening of breast cancer, there are still issues. It is vital to make sure AI does not overlook cancer or cause needless recalls. The aim of this work was to investigate the
Sahar Mansour, Enas Sweed, Mohammed Mohammed Mohammed Gomaa, Samar Ahmed Hussein, Engy Abdallah, Yassmin Mohamed Nada, Rasha Kamal, Ghada Mohamed, Sherif Nasser Taha, Amr Farouk Ibrahim Moustafa   +9 more
doaj   +1 more source

A machine learning approach with verification of predictions and assisted supervision for a rule-based network intrusion detection system [PDF]

, 2008
Network security is a branch of network management in which network intrusion detection systems provide attack detection features by monitorization of traffic data.
Fernández Villamor, José Ignacio, Garijo Ayestaran, Mercedes   +1 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Early Seizure Detection with an Energy-Efficient Convolutional Neural Network on an Implantable Microcontroller

, 2018
Implantable, closed-loop devices for automated early detection and stimulation of epileptic seizures are promising treatment options for patients with severe epilepsy that cannot be treated with traditional means.
Blum, Manuel, Boedecker, Joschka, Dümpelmann, Matthias, Heller, Simon, Hügle, Maria, Manzouri, Farrokh, Schulze-Bonhage, Andreas, Watter, Manuel, Woias, Peter   +8 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Progranulin promotes glioma progression via interaction with cathepsin D and serves as a diagnostic and prognostic biomarker

Discover Oncology
Progranulin (PGRN) plays a crucial role in the progression of various tumor types, making it a potentially valuable biomarker. However, the roles of PGRN vary across tumor types.
Chunming Zhao, Jiamei Guo, Zhong Zhou, Xulong Huang, Yifan Hai, Wenbo Gao, Chaohang Chen, Guokai Dong, Hongxing Cai, Shanshan Li   +9 more
doaj   +1 more source

Identification of atypical mitogen-activated protein kinase MAPK4 as a novel regulator in acute lung injury

Cell & Bioscience, 2020
Background Acute lung injury (ALI) is a serious disease with highly morbidity and mortality that causes serious health problems worldwide. Atypical mitogen activated protein kinases (MAPKs) play critical roles in the development of tissues and have been ...
Ling Mao, Ya Zhou, Longqing Chen, Lin Hu, Shiming Liu, Wen Zheng, Juanjuan Zhao, Mengmeng Guo, Chao Chen, Zhixu He, Lin Xu   +10 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

In-House RT-PCR Assay for Detection of Human Immunodeficiency Virus Type 1 Infection [PDF]

, 2009
Serologic assays are commonly used for screening (ELISA) and for confirmation (Western blot) of HIV-1 infection; however, both assays have potentially yielded the false-positive or false-negative results.
Bela, B. (Budiman), Fatmawati, N. N. (Ni), Ibrahim, F. (Fera), Parwati, K. T. (Ketut), Yasmon, A. (Andi)   +4 more
core