Results 101 to 110 of about 242,070 (288)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Editorial: Working Dogs: Form and Function, Volume II

Frontiers in Veterinary Science, 2021
Nathaniel J. Hall, Cynthia M. Otto, Cynthia M. Otto, Wendy I. Baltzer   +3 more
doaj   +1 more source

Scene Graph Generation via Conditional Random Fields

, 2018
Despite the great success object detection and segmentation models have achieved in recognizing individual objects in images, performance on cognitive tasks such as image caption, semantic image retrieval, and visual QA is far from satisfactory.
Cong, Weilin, Lee, Wang-Chien, Wang, William   +2 more
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Use of a scent-detection dog for sea turtle nest monitoring of three sea turtle species in Florida. [PDF]

PLoS One, 2023
Lindborg RJ, Peruyero P, Witherington BE.   +2 more
europepmc   +1 more source

ParseNet: Looking Wider to See Better [PDF]

, 2015
We present a technique for adding global context to deep convolutional networks for semantic segmentation. The approach is simple, using the average feature for a layer to augment the features at each location.
Berg, Alexander C., Liu, Wei, Rabinovich, Andrew   +2 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Editorial: Canine Olfactory Detection

Frontiers in Veterinary Science, 2020
Claire Guest, Cynthia M. Otto, Cynthia M. Otto   +2 more
doaj   +1 more source

Novel application of a conservation detection dog to recover wildlife telemetry equipment

Animal Biotelemetry
Background Wildlife tracking technologies are increasingly used to study animal behaviour, inform conservation management, and answer fundamental questions in ecology.
Shoshana Rapley, Heather M. McGinness, Claudio Sillero-Zubiri, Micha V. Jackson, Maldwyn J. Evans, Iain J. Gordon, Robert Heinsohn, Adrian D. Manning   +7 more
doaj   +1 more source