Results 131 to 140 of about 240,773 (297)

Editorial: Canine Olfactory Detection

Frontiers in Veterinary Science, 2020
Claire Guest, Cynthia M. Otto, Cynthia M. Otto   +2 more
doaj   +1 more source

Molecular detection of canine Leishmaniasis using conjunctival swab and buffy coat samples [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2016
Many molecular methods have been used for diagnose is of canine leishmaniasis. These methods mainly rely on tissue specimens provided by invasive approaches for molecular detection of leishmaniasis.
mohammadreza ariannejad, gholamreza razmi, javad khoshnegah   +2 more
doaj  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Scent of a frog: Can conservation detection dogs be used to locate endangered amphibians in the wild?

Conservation Science and Practice
In recent years, the potential to locate endangered animals using scent trained detection dogs (conservation detection dogs) has gained attention. Among vertebrates, conservation detection dogs have demonstrated a remarkable capacity to detect the scent ...
Deon J. Gilbert, Michael J. L. Magrath, Luke Edwards, Phillip G. Byrne   +3 more
doaj   +1 more source

The Spectral Energy Distribution and Infrared Luminosities of z ≈ 2 Dust-obscured Galaxies from Herschel and Spitzer [PDF]

, 2012
Dust-obscured galaxies (DOGs) are a subset of high-redshift (z ≈ 2) optically-faint ultra-luminous infrared galaxies (ULIRGs, e.g., L_(IR) > 10^(12) L_☉). We present new far-infrared photometry, at 250, 350, and 500 μm (observed-frame), from the Herschel
Alberts, Stacey, Armus, Lee, Bussmann, R. S., Desai, Vandana, Dey, Arjun, Jannuzi, B. T., Melbourne, J., Pope, Alexandra, Soifer, B. T.   +8 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Dogs for medical detection

, 2017
For many medical conditions, limitations of the existing diagnostic methods can contribute to a high number of deaths. People showing symptoms of cancer are often submitted to a battery of tests that can be a source of anxiety and that sometimes fail to detect early stages of cancer.
openaire   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

COVID Sniffer Dogs: Technical and Ethical Concerns

Frontiers in Veterinary Science, 2021
Biagio D'Aniello, Claudia Pinelli, Mario Varcamonti, Marcello Rendine, Pietro Lombardi, Anna Scandurra   +5 more
doaj   +1 more source