Results 91 to 100 of about 7,324,417 (308)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

National Action Plan for Energy Efficiency, Chapter 6: Energy Efficiency Program Best Practices

open access: yes, 2006
Chapter from the National Action Plan for Energy Efficiency documenting key findings from energy efficiency programs that have been successfully operating for many ...
National Action Plan for Energy Efficiency (U.S.)
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Report of the Energy Efficiency Board. 2011.

open access: yes, 2011
Annual; Began with 2010.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Determination of Gross Beta Activity Excluding 40K in Seawater Around Nuclear Power Plant by Cobalt Sulfide Coprecipitation Method

open access: yesYuanzineng kexue jishu, 2022
In order to simply, quickly and efficiently evaluate the impact of nuclear power plant operation on the surrounding marine environment, a cobalt sulfide coprecipitation method was established to rapidly analyze the gross beta activity excluding 40K in ...
WU Liansheng;HE Yi;SUN Xuefeng;HUANG Yanjun;LI Yuan;LIU Tao;ZENG Fan;CHEN Chaofeng;SHANGGUAN Zhihong;YANG Ziqian
doaj  

Report of the Energy Efficiency Board. 2010.

open access: yes, 2010
Annual; Began with 2010.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Improving the detection capability and efficiency of SARS-CoV-2 RNA specimens by the specimen turn-around process with multi-department cooperation

open access: yesFrontiers in Public Health
ObjectiveImproving the detection capability and efficiency of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA specimens is very important for the prevention and control of the outbreak of Coronavirus disease 2019 (COVID-19).
Chenggui Liu   +12 more
doaj   +1 more source

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