Results 101 to 110 of about 2,243,348 (294)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Improving the detection capability and efficiency of SARS-CoV-2 RNA specimens by the specimen turn-around process with multi-department cooperation

open access: yesFrontiers in Public Health
ObjectiveImproving the detection capability and efficiency of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA specimens is very important for the prevention and control of the outbreak of Coronavirus disease 2019 (COVID-19).
Chenggui Liu   +12 more
doaj   +1 more source

Time-resolved fast-neutron imaging with a pulse-counting image intensifier [PDF]

open access: yes, 2006
A new imaging method that combines high-efficiency fast-neutron detection with sub-ns time resolution is presented. This is achieved by exploiting the high neutron detection efficiency of a thick scintillator and the fast timing capability and ...
Barnstedt, Juergen   +7 more
core  

Comparison of Plastic Antineutrino Detector Designs in the Context of Near Field Reactor Monitoring

open access: yes, 2019
We compare existing segmented plastic antineutrino detectors with our new geometrically improved design for antineutrino detection and light collection efficiency.
Cakir, Altan, Kandemir, Mustafa
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Characterization of some modern scintillators recommended for use on large fusion facilities in γ-ray spectroscopy and tomographic measurements of γ-emission profiles

open access: yesNukleonika, 2017
LaBr3:Ce,CeBr3 and GAGG:Ce scintillators were investigated and the determined characteristics were compared with those obtained for the well-known and widely used CsI:Tl and NaI:Tl crystals. All the detectors were of the same size of 10 × 10 × 5 mm3. The
Sibczynski Pawel   +11 more
doaj   +1 more source

Nondestructive Detection of an Optical Photon

open access: yes, 2013
All optical detectors to date annihilate photons upon detection, thus excluding repeated measurements. Here, we demonstrate a robust photon detection scheme which does not rely on absorption.
Reiserer, Andreas   +2 more
core   +1 more source

Efficient detection of quasiperiodicities in strings

open access: yesTheoretical Computer Science, 1993
A strings \(z\) is quasiperiodic if there is a string \(w\neq z\) such that \(z\) is completely by (possibly overlapping) occurrences of \(w\) in \(z\). In this situation \(w\) is called a quasiperiod of \(z\). If \(z\) is quasiperiodic, then its shortest quasiperiod \(w\) is uniquely determined and is referred to as the quasiperiod of \(z\).
Apostolico, Alberto   +1 more
openaire   +3 more sources

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