Results 121 to 130 of about 2,270,745 (295)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Registration of gamma radiation from the 133Ba and 134Cs decay by detectors of the Pripjat system [PDF]

Nuclear Technology and Radiation Protection
Three NaI(Tl) detectors of 10 cm x 15 cm, in pairs and the three-detector system, were used to acquire spectra of 133Ba and 134Cs, and to consider registration of gamma radiation from de-excitation of their daughters (133Cs and 134Ba ...
Antović Nevenka M., Lalović Nikolija V.   +1 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Method for Determining Iodine Activity Distribution in Activated Carbon Filter Cartridge Source

Journal of Isotopes, 2021
I-131 is an important artificial radionuclide and an important detection object in nuclear facilities. The current mainstream method is to use a uniformly distributed Ba-133 source instead of an iodine source to calibrate the I-131 detection instrument ...
KE Lianbao;XIA Wen;YE Hongsheng;SONG Xinpeng;XU Lijun;LIN Min;CHEN Kesheng
doaj  

Nanostructures for highly efficient infrared detection

SPIE Proceedings, 2017
We propose a high sensitivity photodetection tool at near-infrared frequencies, based on a principle of slowed- and stopped-light in chirped photonic micro/nano-structures. The main goal is to substantially increase the efficiency of photodetection and provide chromatic resolution in infrared photodetection.
Gailevicius, D., Hayran, Z., Turduev, Mirbek, Kurt, Hamza, Juodkazis, S., Malinauskas, M., Mizeikis, V., Staliunas, Kestutis   +7 more
openaire   +4 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Monte Carlo simulation of HPGe gamma-spectrometry systems

The Journal of Engineering, 2019
In order to obtain the relationship between energy and channel, the suitable radionuclides are chosen to calibrate. The result shows a goodness of fitting.
Dongjie Hou, Siming Guo, Jianwei Huang, Chong Wu, Jinjie Wu   +4 more
doaj   +1 more source

A High-Detection-Efficiency Optoelectronic Device for Trace Cadmium Detection. [PDF]

Sensors (Basel), 2022
Gu H, Wang L.
europepmc   +1 more source

Efficient MIMO Detection Metho

, 2014
For the past decades, the demand in transferring large amounts of data rapidly and reliably has been increasing drastically.
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source