Results 171 to 180 of about 11,794,013 (339)

Time-domain based evaluation of detection efficiency in liquid scintillation counting. [PDF]

Sci Rep, 2021
Mitev K, Dutsov C, Cassette P, Sabot B.
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

2.5D microscopy with polarization independent SLM for enhanced detection efficiency and aberration correction. [PDF]

Opt Express, 2021
Ren J, Han KY.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Quantification of Light Scattering Detection Efficiency and Background in Flow Cytometry. [PDF]

Cytometry A, 2021
de Rond L, Coumans FAW, Welsh JA, Nieuwland R, van Leeuwen TG, van der Pol E.   +5 more
europepmc   +1 more source

Intelligent Green Efficiency for Intrusion Detection

Artificial Intelligence (AI) has emerged in popularity recently, recording great progress in various industries. However, the environmental impact of AI is a growing concern, in terms of the energy consumption and carbon footprint of Machine Learning (ML) and Deep Learning (DL) models, making essential investigate Green AI, an attempt to reduce the ...
Pedro Pereira, Paulo Mendes, João Vitorino, Eva Maia, Isabel Praça   +4 more
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Detection Efficiency of Ag Nanoparticle Labels for a Heart Failure Marker Using Linear and Square-Wave Anodic Stripping Voltammetry. [PDF]

Biosensors (Basel), 2022
Raj N, Crooks RM.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Detection performance analysis of advanced direction time lightning detection system in China

Frontiers in Earth Science
In order to study the detection performance of the Advanced Direction Time Lightning Detection System (ADTD) over mainland China, the relationship between the detection efficiency (DE) and distance for ADTD sensor is analyzed using lightning location ...
Hualiang Zhu, Wenjing Pang, Fengjiao Chen, Fengjiao Chen, Miaomiao Zhang, Jing Wang, Zhichao Wang   +6 more
doaj   +1 more source