Statistical treatment of geochemical data with observations below the detection limit
C. F. Chung
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Limits of detection of polydimethylsiloxane in29Si NMR spectroscopy [PDF]
Darlene J. Semchyschyn +1 more
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Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Snow Surface Microbial Diversity at the Detection Limit within the Vicinity of the Concordia Station, Antarctica. [PDF]
Napoli A +5 more
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Assay of antibiotic detection limits in cow's milk model samples and comparison of sensitivity of various detection systems (disk diffusion method, Delvotest SP and Penzym S 100). [PDF]
B. Hozóvá, M. Kratmüllerová
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
1H NMR Spectroscopic Microanalysis Using Precision Coaxial Tubing and the Limit of Detection.
Koichi Hatada +2 more
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Limits of homology detection by pairwise sequence comparison [PDF]
Rainer Spang, Martin Vingron
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