Results 191 to 200 of about 1,026,341 (311)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Boosting the velocity detection limit of 3D single-cell tracking time-lapse MRI by balanced SSFP imaging. [PDF]

Magn Reson Med
Wilken E, Havlas A, Wachsmuth L, Masthoff M, Diwoky C, Faber C.   +5 more
europepmc   +1 more source

Real-Time Ellipsometric Surface Plasmon Resonance Sensor Using Polarization Camera May Provide the Ultimate Detection Limit. [PDF]

Biosensors (Basel), 2023
Vashistha N, Abuleil MJ, Shrivastav AM, Bajaj A, Abdulhalim I.   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Semiconductor-Bimetallic Plasmonic Heterojunction ZnO-Ag-Cu as Reusable SERS Substrate with Attomolar Detection Limit. [PDF]

Chem Asian J
Behera R, Nag A.
europepmc   +1 more source

Breaking Down SERS Detection Limit: Engineering of a Nanoporous Platform for High Sensing and Technology. [PDF]

Nanomaterials (Basel), 2022
Scaglione F, Battezzati L, Rizzi P.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Unique Organic-Inorganic Hybrid Copper(I) Phosphate with Ultralow Ractopamine Detection Limit and In Situ Sensing Ability. [PDF]

Inorg Chem
Xie JF, Wei PC, Li Y, Chang CC, Chang KC, Lu CP, Hsu T, Tzou DM, Tu HL, Wang CM.   +9 more
europepmc   +1 more source

Elicitation of Innate Immunity by a Bacterial Volatile 2-Nonanone at Levels below Detection Limit in Tomato Rhizosphere. [PDF]

Mol Cells, 2022
Riu M, Kim MS, Choi SK, Oh SK, Ryu CM.
europepmc   +1 more source

Coded Modulation Assisted Genetic Algorithm Based Multiuser Detection for CDMA Systems

, 2002
In this contribution we propose a novel Coded Modulation assisted Genetic Algorithm based Multiuser Detection (CM-GA-MUD) scheme for synchronous CDMA systems.
Ng, S.X., Ng, S. X., Hanzo, L., Yen, K.
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