Results 181 to 190 of about 4,854,135 (253)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Rankings of tuberculosis antibiotic treatment regimens are sensitive to spatial scale, detection limit, and initial host bacterial burden. [PDF]

J Theor Biol
Michael CT, Budak M, Maiello P, Kracinovsky K, Rodgers M, Tomko J, Lin PL, Flynn J, Linderman JJ, Kirschner D.   +9 more
europepmc   +1 more source

Rethinking COVID-19 test sensitivity-a strategy for improving the detection limit. [PDF]

Pan Afr Med J, 2021
Akhtar MK, Leung RK, Khan G.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

High-Sensitivity, Low Detection Limit, and Fast Ammonia Detection of Ag-NiFe₂O₄ Nanocomposite and DFT Study. [PDF]

Nanomaterials (Basel)
Hao X, Sun Y, Liu Z, Jiao G, Zhang D.
europepmc   +1 more source

Determination of X-ray detection limit and applications in perovskite X-ray detectors. [PDF]

Nat Commun, 2021
Pan L, Shrestha S, Taylor N, Nie W, Cao LR.   +4 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Extending the detection limit: innovations in infrared quantum dot photodetectors reaching up to 18 μm. [PDF]

Light Sci Appl
Wang CW, Wang QJ.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Highly stable bismuth-chloride perovskite X-ray direct detectors with an ultralow detection limit. [PDF]

Chem Sci
Chen H, Han Q, Qin H, Shen Y, Lv H, Liu Y, Du L, Wang Y, He Y, Ning W.   +9 more
europepmc   +1 more source