Results 71 to 80 of about 541,940 (268)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Detection Probability and Bias in Machine-Learning-Based Unoccupied Aerial System Non-Breeding Waterfowl Surveys

Drones
Unoccupied aerial systems (UASs) may provide cheaper, safer, and more accurate and precise alternatives to traditional waterfowl survey techniques while also reducing disturbance to waterfowl.
Reid Viegut, Elisabeth Webb, Andrew Raedeke, Zhicheng Tang, Yang Zhang, Zhenduo Zhai, Zhiguang Liu, Shiqi Wang, Jiuyi Zheng, Yi Shang   +9 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Range‐wide population size of the lesser prairie‐chicken: 2012 and 2013

Wildlife Society Bulletin, 2014
We flew aerial line‐transect surveys to estimate the range‐wide population size of lesser prairie‐chickens (Tympanuchus pallidicinctus) in the Great Plains, United States in 2012 and 2013.
Lyman McDonald, Grant Beauprez, Grant Gardner, Jim Griswold, Christian Hagen, Fawn Hornsby, David Klute, Sean Kyle, James Pitman, Troy Rintz, Doug Schoeling, Bill Van Pelt   +11 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Timing matters: cloud cover and date influence probability of detecting nesting Chimney Swifts (Chaetura pelagica)

Avian Conservation and Ecology, 2019
One third of bird species in North America need immediate conservation action. Effective management and recovery actions for species of conservation concern require accurate methods of monitoring species occurrence that limit the incidence of ...
Elisabeth F. Purves, C. Myles. Falconer, Douglas C. Tozer, Kristyn Richardson   +3 more
doaj  

Factors affecting the occupancy of sloth bear and its detection probability in Parsa-Koshi Complex, Nepal. [PDF]

Ecol Evol, 2023
Sharma HP, Katuwal HB, Bhattarai BP, Bhandari S, Adhikari D, Aryal B, Tamang K, Nepali A, Kc S, Baral BD, Devkota S, Koirala S, Mandal DN, Regmi S.   +13 more
europepmc   +1 more source

OPTIMAL INVESTIGATING SEARCH MAXIMIZING THE DETECTION PROBABILITY

Journal of the Operations Research Society of Japan, 1997
Summary: We deal with a two-stage search consisting of the broad search and the investigating search, and derive conditions of an optimal investigating search plan maximizing the detection probability of a target. We consider a search for a target in an area under a restriction of search time.
Iida, Koji, Hohzaki, Ryusuke, Kaiho, Takesi   +2 more
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source