Results 61 to 70 of about 116,850 (264)

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Wide Dynamic Range, High Uniformity Spectral Irradiance Source for Calibration of Scientific-Grade, Large-Size Space Detectors

Remote Sensing
In order to meet the high uniformity calibration requirements for scientific-grade, large-size space detectors used in the CHES Extrasolar Planet Exploration Mission, this paper presents the design of a wide dynamic range, high uniformity spectral ...
Deyao Kong, Yinlin Yuan, Haitao Li, Wenchao Zhai, Xiaobing Zheng   +4 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Calibration of the IMB detector

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1995
The IMB detector (named after its founding institutions: University of California, Irvine, the University of Michigan and Brookhaven National Laboratory) collected data on a wide range of phenomena for over eight years. It was the first and the largest of the ring imaging water Cherenkov detectors.
R. Becker-Szendy, R.M. Bionta, C.B. Bratton, D. Casper, R. Claus, B. Cortez, S.T. Dye, S. Errede, G.W. Foster, W. Gajewski, K. Ganezer, M. Goldhaber, T.J. Haines, P.G. Halverson, E. Hazen, T.W. Jones, D. Kielczewska, W.R. Kropp, J.G. Learned, J.M. Losecco, S. Matsuno, J. Matthews, G. McGrath, C. McGrew, R. Miller, M.S. Mudan, H.S. Park, L.R. Price, F. Reines, J. Schultz, S. Seidel, D. Sinclair, H.W. Sobel, J.L. Stone, L.R. Sulak, R. Svoboda, G. Thornton, J.C. van der Velde, C. Wuest   +38 more
openaire   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Development and Validation of a Digitizer-Based TCSPC System for Scintillation Decay Time Analysis via an Extended Convolution Model

Sensors
The development of high-fidelity digital twins for scintillation spectrometer detectors demands precise experimental characterization of timing parameters.
Qianqian Zhou, Zhijie Yang, Wenhui Li, Juncheng Liang, Wuyun Xiao   +4 more
doaj   +1 more source

Development of [²²⁵Ac]Ac-DOTA-C595 as radioimmunotherapy of pancreatic cancer: in vitro evaluation, dosimetric assessment and detector calibration. [PDF]

EJNMMI Radiopharm Chem, 2023
Hull A, Hsieh W, Borysenko A, Tieu W, Bartholomeusz D, Bezak E.   +5 more
europepmc   +1 more source