Results 51 to 60 of about 553,105 (269)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Quasi-complete Latin squares: construction and randomization
, 1984 A general method for constructing quasi-complete Latin squares based on groups is given. This method leads to a relatively straightforward way of counting the number of inequivalent quasi-complete Latin squares of side at most 9.
Bailey, Rosemary Anne +2 more
core +1 more source
Detection of nitrite by flow injection analysis using a novel paired emitter-detector diode (PEDD) as a photometric detector [PDF]
, 2007 An inexpensive flow injection analysis system for determining low concentration levels of nitrite employing the Griess reagent spectrophotometric method is reported.
O'Toole, Martina +8 more
core +2 more sources
康复学报, 2017 Objective:To investigate the effects of core muscle acupuncture on the trunk stability control in children with spastic cerebral palsy.Methods:Thirty cases of spastic cerebral palsy children with sitting disequilibrium were selected and divided into ...
Jie ZHANG +5 more
doaj
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Randomization with Asymmetric Information [PDF]
It is by now well-known that, in the presence of moral hazard or adverse selection, randomization of insurance premia and benefits may be Pareto efficient.
Richard J. Arnott, Joseph E. Stiglitz
core
X-ray detector based on a bulk micromachined photodiode combined with a scintillating crystal [PDF]
, 2003 This paper reports the design, fabrication, assembly and testing of a x-ray detector based on a bulk micromachined photodiode (BMMPD) with a cavity filled with a scintillating crystal.
Ramos, N. F. +15 more
core +1 more source
Feasibility of Randomized Detector Tuning for Attack Impact Mitigation
CoRRThis paper considers the problem of detector tuning against false data injection attacks. In particular, we consider an adversary injecting false sensor data to maximize the state deviation of the plant, referred to as impact, whilst being stealthy. To minimize the impact of stealthy attacks, inspired by moving target defense, the operator randomly ...
Sribalaji Coimbatore Anand +2 more
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source