Results 71 to 80 of about 6,996 (263)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Asynchronous Consensus with Bounded Memory. [PDF]
, 2016 International audienceWe present here a bounded memory size Obstruction-Free consensus algorithm for the asynchronous shared memory model. More precisely for a set of n processes, this algorithm uses n+2n+2 multi-writer multi-reader registers, each of ...
Delporte-Gallet, Carole +3 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Randomized Anagram Revisited [PDF]
, 2014 When compared to signature-based Intrusion Detection Systems (IDS), anomaly detectors present the potential advantage of detecting previously unseen attacks, which makes them an attractive solution against zero-day exploits and other attacks for which a ...
Pastrana Portillo, Sergio +7 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Bolt Detection and Position Estimation Using Domain Randomization [PDF]
, 2018 This item is available only to currently enrolled UTSA students, faculty or staff. To download, navigate to Log In in the top right-hand corner of this screen, then select Log in with my UTSA ID.Current robot automation efforts of aircraft fuselage layer
Ameperosa, Ezra Tima
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Screening the recognition properties of peptide hormone sequence mutants by analytical high performance liquid affinity chromatography on immobilized neurophysin [PDF]
, 1988 Analytical high performance liquid affinity chromatography with immobilized neurophysin was used as a molecular screen to evaluate the effects of peptide hormone structure modification on protein recognition.
Irwin M. Chaiken +2 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Optimal stochastic approaches for signal detection and estimation under inequality constraints [PDF]
, 2012 Cataloged from PDF version of article.Includes bibliographical references leaves 141-153.Fundamental to the study of signal detection and estimation is the design of optimal procedures that operate on the noisy observations of some random phenomenon ...
Dülek, Berkan
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