Results 81 to 90 of about 553,105 (269)

X-ray detector on 2U cubesat BeEagleSAT of QB50 [PDF]

open access: yes, 2013
BeEagleSAT is a 2 Unit cubesat to be launched within the EU FP7 project QB 50. It is been produced by Istanbul Technical University and Turkish Air Force Academy.
Ümit, Ertan   +5 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Intermediate Silicon Layers Detector, rivelatore in silicio realizzato per la presa dati "Run II" (2001-2011) dell'esperimento Collider Detector at Fermilab (CDF)

open access: yes, 1997
Negli anni 1997-1998 sono stato dipendente del Fermi National Accelerator Laboratory e ho contruito alla progettazione e costruzione del rivelatore successivamente installato nell'esperimento CDF per la presa dati "Run II" del Tevatron degli anni 2001 ...
DONATI, SIMONE   +1 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

DELPHI Barrel Ring Imaging Cherenkov Detector

open access: yes, 2001
DELPHI was one of the four experiments installed at the LEP particle accelerator from 1989 - 2000. This is a piece of the Barrel Ring Imaging Cherenkov detector which was used to identify particles in DELPHI.It measured the Cherenkov light emitted when ...

core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Study protocol: randomization

open access: yes, 2017
Randomization ...
Savadogo, Patrice
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

4000 jaar metaal in Nederland

open access: yes, 1999
il
Jager, Alexander
core  

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