Results 81 to 90 of about 553,105 (269)
X-ray detector on 2U cubesat BeEagleSAT of QB50 [PDF]
BeEagleSAT is a 2 Unit cubesat to be launched within the EU FP7 project QB 50. It is been produced by Istanbul Technical University and Turkish Air Force Academy.
Ümit, Ertan +5 more
core +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Negli anni 1997-1998 sono stato dipendente del Fermi National Accelerator Laboratory e ho contruito alla progettazione e costruzione del rivelatore successivamente installato nell'esperimento CDF per la presa dati "Run II" del Tevatron degli anni 2001 ...
DONATI, SIMONE +1 more
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
DELPHI Barrel Ring Imaging Cherenkov Detector
DELPHI was one of the four experiments installed at the LEP particle accelerator from 1989 - 2000. This is a piece of the Barrel Ring Imaging Cherenkov detector which was used to identify particles in DELPHI.It measured the Cherenkov light emitted when ...
core
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source

