Results 111 to 120 of about 256,768 (386)
Advanced Science, EarlyView.Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li +16 more
wiley +1 more source
Asian Nursing Research, 2010 This study compared the catheter-associated urinary tract infection (CAUTI) rates resulting from the use of four perineal care agents (soap-and-water, skin cleansing foam, 10% povidone-iodine, and normal saline) among patients in intensive care units ...
Ihnsook Jeong, PhD, RN +6 more
doaj +1 more source
Reviewing factors affecting the effectiveness of decentralised domestic wastewater treatment systems for phosphorus and pathogen removal [PDF]
, 2017 Environmental pollution and risks to human health can result from diffuse sources of pollution originating from decentralised wastewater treatment systems (DWTS).
Akunna, Joseph C. +2 more
core +3 more sources
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
Advanced Science, EarlyView.The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia +12 more
wiley +1 more source
RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella [PDF]
, 2018 Brucellaceae are stealthy pathogens with the ability to survive and replicate in the host in the context of a strong immune response. This capacity relies on several virulence factors that are able to modulate the immune system and in their structural ...
Altabe, Silvia Graciela +10 more
core +1 more source
Use of anionic denaturing detergents to purify insoluble proteins after overexpression
BMC Biotechnology, 2012 BackgroundMany proteins form insoluble protein aggregates, called “inclusion bodies”, when overexpressed in E. coli. This is the biggest obstacle in biotechnology.
Benjamin Schlager +2 more
semanticscholar +1 more source
EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation
Advanced Science, EarlyView.Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi +12 more
wiley +1 more source
Method for decellularizing skeletal muscle without detergents or proteolytic enzymes.
Tissue Engineering. Part C, Methods, 2011 Decellularized skeletal muscle is a promising model that can be used to study cell-matrix interactions and changes that occur in muscle extracellular matrix (ECM) in myopathies and muscle wasting diseases.
Allison R Gillies +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.A photovoltaic/photomultiplication dual‐mode organic photodetector is developed by integrating two different organic bulk‐heterojunctions, one introduces the photovoltaic effect, and the other triggers photomultiplication charge generation in the stacked device at different voltage polarities.
Xin Hu +6 more
wiley +1 more source