Results 141 to 150 of about 1,507,905 (292)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Efficiency of natural wood extractives as wood preservatives against termite attack
Maderas: Ciencia y Tecnología, 2012 Wood extractives play a major role in the protection of wood against termite and fungal attack. Wood extractives from three hard wood species of Milicia excelsa, Albizia coriaria and Markhamia lutea that are known to be very resistant against termite ...
A Syofuna, A.Y Banana, G Nakabonge
doaj
Assessing Long-Term Fiscal Developments: Evidence from Portugal [PDF]
Drawing on quarterly data for Portugal, we use a Three-Stage Least Square method and a system of equations to recursively estimate two components of fiscal policy – responsiveness and persistence – and to infer about the sources of fiscal deterioration ...
António Afonso, Ricardo M. Sousa
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Efficiency of natural wood extractives as wood preservatives against termite attack
Maderas: Ciencia y Tecnología, 2014 Wood extractives play a major role in the protection of wood against termite and fungal attack. Wood extractives from three hard wood species of Milicia excelsa, Albizia coriaria and Markhamia lutea that are known to be very resistant against termite ...
A. Syofuna, A.Y. Banana, G. Nakabonge
doaj
Using financial data to identify changes in bank condition [PDF]
An empirical study using an early-warning bank failure prediction model and call-report data to predict deterioration in a bank's condition.Bank supervision ; Bank ...
Gary Whalen, James B. Thomson
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Deterioration after Mitral Valvotomy--I [PDF]
BMJ, 1962 C P, LOWTHER, R W, TURNER
openaire +5 more sources